{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T08:13:46Z","timestamp":1776154426015,"version":"3.50.1"},"reference-count":27,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,7]],"date-time":"2021-02-07T00:00:00Z","timestamp":1612656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001774","name":"New Jersey Health Foundation","doi-asserted-by":"publisher","award":["PC53-19"],"award-info":[{"award-number":["PC53-19"]}],"id":[{"id":"10.13039\/100001774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Sensory feedback from wearables can be effective to learn better movement through enhanced information and engagement. Facilitating greater user cognition during movement practice is critical to accelerate gains in motor function during rehabilitation following brain or spinal cord trauma. This preliminary study presents an approach using an instrumented glove to leverage sense of agency, or perception of control, to provide training feedback for functional grasp. Seventeen able-bodied subjects underwent training and testing with a custom-built sensor glove prototype from our laboratory. The glove utilizes onboard force and flex sensors to provide inputs to an artificial neural network that predicts achievement of \u201csecure\u201d grasp. Onboard visual and audio feedback was provided during training with progressively shorter time delay to induce greater agency by intentional binding, or perceived compression in time between an action (grasp) and sensory consequence (feedback). After training, subjects demonstrated a significant reduction (p &lt; 0.05) in movement pathlength and completion time for a functional task involving grasp-move-place of a small object. Future work will include a model-based algorithm to compute secure grasp, virtual reality immersion, and testing with clinical populations.<\/jats:p>","DOI":"10.3390\/s21041173","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T04:33:46Z","timestamp":1612931626000},"page":"1173","update-policy":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Training with Agency-Inspired Feedback from an Instrumented Glove to Improve Functional Grasp Performance"],"prefix":"10.3390","volume":"21","author":[{"given":"Mingxiao","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ 07030, USA"},{"name":"Movement Control Rehabilitation (MOCORE) Laboratory, Altorfer Complex, Stevens Institute of Technology, Hoboken, NJ 07030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Wilder","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ 07030, USA"},{"name":"Movement Control Rehabilitation (MOCORE) Laboratory, Altorfer Complex, Stevens Institute of Technology, Hoboken, NJ 07030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Sanford","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ 07030, USA"},{"name":"Movement Control Rehabilitation (MOCORE) Laboratory, Altorfer Complex, Stevens Institute of Technology, Hoboken, NJ 07030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/orcid.org\/0000-0002-9936-1249","authenticated-orcid":false,"given":"Soha","family":"Saleh","sequence":"additional","affiliation":[{"name":"Center for Mobility and Rehabilitation Engineering Research, Advanced Rehabilitation Neuroimaging Laboratory, Kessler Foundation, East Hanover, NJ 07936, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/orcid.org\/0000-0003-3085-2194","authenticated-orcid":false,"given":"Noam Y.","family":"Harel","sequence":"additional","affiliation":[{"name":"Spinal Cord Damage Research Center, James J. 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Neural Repair"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3758\/s13423-012-0333-8","article-title":"Augmented visual, auditory, haptic, and multimodal feedback in motor learning: A review","volume":"20","author":"Sigrist","year":"2013","journal-title":"Psychon Bull. Rev."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Clark, D., Schumann, F., and Mostofsky, S.H. (2015). Mindful movement and skilled attention. Front. Hum. Neurosci., 9.","DOI":"10.3389\/fnhum.2015.00297"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1179\/2045772314Y.0000000194","article-title":"Physical therapy after spinal cord injury: A systematic review of treatments focused on participation","volume":"37","author":"Sliwinski","year":"2014","journal-title":"J. Spinal Cord Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/NPT.0b013e31814a6493","article-title":"Attention and dual-task conditions: Physical therapy implications for individuals with acquired brain injury","volume":"31","author":"McCulloch","year":"2007","journal-title":"J. Neurol. Phys. Therapy"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-3-319-03017-3_10","article-title":"Classifying Human Hand Use and the Activities of Daily Living","volume":"Volume 95","author":"Balasubramanian","year":"2014","journal-title":"The Human Hand as an Inspiration for Robot Hand Development"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/WCO.0000000000000380","article-title":"Behavioral self-management strategies for practice and exercise should be included in neurologic rehabilitation trials and care","volume":"29","author":"Dobkin","year":"2016","journal-title":"Curr. Opin. Neurol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1177\/1545968306286914","article-title":"Sensorimotor Training in a Virtual Reality Environment: Does It Improve Functional Recovery Poststroke?","volume":"20","author":"Merians","year":"2006","journal-title":"Neurorehabilit. Neural Repair"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12984-018-0391-x","article-title":"Assisting hand function after spinal cord injury with a fabric-based soft robotic glove","volume":"15","author":"Cappello","year":"2018","journal-title":"J. Neuroeng. Neurorehabilit."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s12541-012-0107-2","article-title":"Current hand exoskeleton technologies for rehabilitation and assistive engineering","volume":"13","author":"Heo","year":"2012","journal-title":"Int. J. Precis. Eng. Manuf."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"12972","DOI":"10.1109\/JSEN.2020.3001982","article-title":"A Robust Data-Driven Soft Sensory Glove for Human Hand Motions Identification and Replication","volume":"20","author":"Nassour","year":"2020","journal-title":"IEEE Sens. J."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Weber, P., Rueckert, E., Calandra, R., Peters, J., and Beckerle, P. (2016, January 26\u201331). A low-cost sensor glove with vibrotactile feedback and multiple finger joint and hand motion sensing for human-robot interaction. Proceedings of the 2016 25th IEEE International Symposium on Robot and Human Interactive Communication (RO-MAN), New York, NY, USA.","DOI":"10.1109\/ROMAN.2016.7745096"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10514-014-9402-3","article-title":"Grasp quality measures: Review and performance","volume":"38","author":"Roa","year":"2015","journal-title":"Auton. Robot."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"036025","DOI":"10.1088\/1741-2552\/aa6802","article-title":"Deep learning-based artificial vision for grasp classification in myoelectric hands","volume":"14","author":"Ghazaei","year":"2017","journal-title":"J. Neural Eng."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.3389\/fpsyg.2016.01272","article-title":"What Is the Sense of Agency and Why Does it Matter?","volume":"7","author":"Moore","year":"2016","journal-title":"Front. Psychol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Nataraj, R., Sanford, S., Shah, A., and Liu, M. (2020). Agency and Performance of Reach-to-Grasp with Modified Control of a Virtual Hand: Implications for Rehabilitation. Front. Hum. Neurosci., 14.","DOI":"10.3389\/fnhum.2020.00126"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nn827","article-title":"Voluntary action and conscious awareness","volume":"5","author":"Haggard","year":"2002","journal-title":"Nat. Neurosci."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1177\/1545968306297871","article-title":"Functional electrical stimulation enhancement of upper extremity functional recovery during stroke rehabilitation: A pilot study","volume":"21","author":"Alon","year":"2007","journal-title":"Neurorehabilit. Neural Repair"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/PEP.0b013e3181a3afc2","article-title":"A pilot study: Coordination of precision grip in children and adolescents with high functioning autism","volume":"21","author":"David","year":"2009","journal-title":"Pediatric Phys. Ther."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/1545968309345268","article-title":"The effects of bilateral arm training on motor control and functional performance in chronic stroke: A randomized controlled study","volume":"24","author":"Lin","year":"2010","journal-title":"Neurorehabilit. Neural Repair"},{"key":"ref_21","unstructured":"U.S. Food & Drug (2021, January 27). Information Sheet Guidance for Institutional Review Boards (IRBs), Clinical Investigators, and Sponsors, Available online: https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/www.fda.gov\/science-research\/guidance-documents-including-information-sheets-and-notices\/information-sheet-guidance-institutional-review-boards-irbs-clinical-investigators-and-sponsors."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/105294199277860","article-title":"The international conference on harmonization good clinical practice guideline","volume":"6","author":"Dixon","year":"1999","journal-title":"Quality Assurance"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Corbetta, D., Sirtori, V., Castellini, G., Moja, L., and Gatti, R. (2015). Constraint-induced movement therapy for upper extremities in people with stroke. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD004433.pub3"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1080\/10255842.2013.820722","article-title":"Integration of marker and force data to compute three-dimensional joint moments of the thumb and index finger digits during pinch","volume":"18","author":"Nataraj","year":"2015","journal-title":"Comput. Methods Biomech. Biomed. Eng."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-2923.2009.03421.x","article-title":"Motor skill learning and performance: A review of influential factors","volume":"44","author":"Wulf","year":"2010","journal-title":"Med. Educ."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Dewey, J.A., and Knoblich, G. (2014). Do implicit and explicit measures of the sense of agency measure the same thing?. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0110118"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Enders, L.R., Hur, P., Johnson, M.J., and Seo, N.J. (2013). Remote vibrotactile noise improves light touch sensation in stroke survivors\u2019 fingertips via stochastic resonance. J. Neuroeng. Rehabil., 8.","DOI":"10.1186\/1743-0003-10-105"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/www.mdpi.com\/1424-8220\/21\/4\/1173\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:20:57Z","timestamp":1760160057000},"score":1,"resource":{"primary":{"URL":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/www.mdpi.com\/1424-8220\/21\/4\/1173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,7]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,2]]}},"alternative-id":["s21041173"],"URL":"https:\/\/summer-heart-0930.chufeiyun1688.workers.dev:443\/https\/doi.org\/10.3390\/s21041173","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,7]]}}}