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{{short description|Welsh cardiologist (1881-1945)}}
[[File:Thomas Lewis (cardiologist).jpg|thumb|upright|Thomas Lewis]]▼
{{Use dmy dates|date=June 2014}}▼
[[File:Thomas Lewis (cardiologist)2.jpg|thumb|upright|Thomas Lewis]]▼
{{Infobox officeholder
'''Sir Thomas Lewis''', [[Order of the British Empire|CBE]], [[Fellow of the Royal Society|FRS]], [[Fellow of the Royal College of Physicians|FRCP]]<ref name="frs">{{Cite journal | last1 = Drury | first1 = A. N. | last2 = Grant | first2 = R. T. | doi = 10.1098/rsbm.1945.0012 | title = Thomas Lewis. 1881-1945 | journal = [[Obituary Notices of Fellows of the Royal Society]] | volume = 5 | issue = 14 | pages = 179 | year = 1945 | pmid = | pmc = }}</ref> (26 December 1881 – 17 March 1945) was a British [[cardiologist]] (although he personally disliked the term, preferring [[cardiovascular disease]] specialist<ref name="DNB" />).<ref name="DNB" /><ref>{{Cite journal ▼
| honorific_prefix =
| last1 = Cygankiewicz | first1 = I. ▼
|
| honorific_suffix = {{postnominals|country=GBR|size=100%|CBE|FRS|FRCP}}
| journal = Cardiology journal ▼
| volume = 14 ▼
|
|
| office = Physician to [[University College Hospital]]
| year = 2007 ▼
| term_start =
| term_end =
| birth_name =
| birth_date = 26 December 1881
| birth_place = [[Taffs Well]], [[Cardiff]], Wales
| death_date = {{Death date and age|1945|03|17|1881|12|26|df=yes}}
| death_place = [[Loudwater, Hertfordshire]], England
| nationality = British
| other_names =
| occupation = [[Cardiologist]]
| years_active =
| known_for =
| notable_works =
}}
▲'''Sir Thomas Lewis'''
| title = Sir Thomas Lewis (1881-1945)
| issue = 6
| pages = 605–606
| pmid = 18651531
}}</ref><ref>{{Cite journal
| last1 = Pearce | first1 = J. M. S.
| title = Sir Thomas Lewis MD, FRS. (1881–1945)
| doi = 10.1007/s00415-006-0166-3
| journal = Journal of Neurology
| volume = 253
| issue = 9
| pages = 1246–1247
| year = 2006
| pmid = 16990996
|
}}</ref><ref>{{Cite journal
| last1 = Haas | first1 = L. F.
| title = Sir Thomas Lewis 1881-1945
| doi = 10.1136/jnnp.2004.055269
| journal = Journal of Neurology, Neurosurgery & Psychiatry
| volume = 76
| issue = 8
| page = 1157
| year = 2005
| pmid = 16024897
| pmc =1739765
}}</ref><ref>{{Cite journal
| last1 = Krikler | first1 = D. M.
| title = Thomas Lewis, a father of modern cardiology
| journal = Heart
| volume = 77
| issue = 2
| pages = 102–103
| year = 1997
| pmid = 9068389
| pmc = 484655
| doi=10.1136/hrt.77.2.102
}}</ref><ref>{{cite book |author=
| last1 = Hollman | first1 = A.
| title = Sir Thomas Lewis: Clinical scientist and cardiologist, 1881-1945
| journal = [[Journal of
| volume = 2
| issue = 2
| pages = 63–70
| year = 1994
| pmid = 11639239
| doi = 10.1177/096777209400200201
| s2cid = 22520472
}}</ref> He coined the term "[[clinical science]]" and is also known for the Lewis P Factor.<ref name="DNB">Biography, ''[[Oxford Dictionary of National Biography]]''</ref><ref>{{Cite journal |last=Birdsong |first=William T. |date=November 18, 2010 |title=Sensing Muscle Ischemia: Coincident Detection of Acid and ATP via Interplay of Two Ion Channels |url=https://www.cell.com/neuron/fulltext/S0896-6273(10)00771-3?_returnURL=https%3A%2F%2Fsummer-heart-0930.chufeiyun1688.workers.dev%3A443%2Fhttps%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627310007713%3Fshowall%3Dtrue |journal=Neuron |volume=68 |issue=4 |pages=739-749 |via=Cell Press}}</ref>
==Early life and education==
Lewis was born in [[Taffs Well]],<ref>{{cite journal|title=Obituary|journal=British Medical Journal|date=March 31, 1945|volume=461|issue=British Medical Journal|pages=1|url=http://www.bmj.com/content/1/4395/461|
==Career==
While still a house physician, Lewis began [[physiology|physiological]] research, carrying out fundamental research on the heart, the [[pulse]] and [[blood pressure]]. From 1906, he corresponded with the Dutch physiologist [[Willem Einthoven]] concerning the latter's invention of the string galvanometer and [[electrocardiography]], and Lewis pioneered its use in clinical settings. Accordingly, Lewis is considered the "father of clinical cardiac electrophysiology". The first use of electrocardiography in clinical medicine was in 1908. In that year, Thomas Lewis and [[Arthur MacNalty]] (later the [[Chief Medical Officer (United Kingdom)|Chief Medical Officer of the United Kingdom]]) employed electrocardiography to diagnose [[heart block]].<ref>”A note on the simultaneous occurrence of sinus and ventricular rhythm in man”, Lewis T, Macnalty AS, ''J. Physiol.'' 1908 Dec 15;37(5–6):445-58</ref> In 1909, with [[Sir James Mackenzie|James MacKenzie]], Lewis founded the journal ''Heart: A Journal for the Study of the Circulation'', which he renamed ''[[Clinical Science (journal)|Clinical Science]]'' in 1933. In 1913, he published the book
[[File:The soldier's heart and the effort syndrome Wellcome L0027240.jpg|thumb|The soldier's heart and the effort syndrome]][[File:Thomas Lewis electrocardiograph (2).jpeg|alt=Electrocardiograph, a large wooden, workbench-like machine, with metal switches on the front face|thumb|Electrocardiograph, used by Sir Thomas Lewis at University College Hospital, London, by the Cambridge Instrument Co. 1930.]]
During the [[First World War]], Lewis worked at the [[Military Heart Hospital]] in [[Hampstead]] and was appointed
After the war,
▲After the war, he established the clinical research department at UCH and continued his work on [[cardiac arrhythmia]]. In 1925 he switched his focus from cardiography to vascular reactions of the skin. In 1917 he had shown that [[capillaries]] had independent contractions and he now investigated the response of the skin to injury, leading to the 1927 monograph ''The Blood Vessels of the Human Skin and their Responses''. He was awarded the [[Royal Society]]'s [[Royal Medal]] in 1927 "for his researches on the vascular system, following upon his earlier work on the mammalian heart-beat." Next, he switched his focus to [[peripheral vascular disease]], especially [[Raynaud's disease]], and finally to the mechanism of pain, summarising his findings in ''Pain'' in 1942. His 1932 book ''Diseases of the Heart'' became a standard medical text. In 1930 he described the [[Hunting reaction]], alternating vasodilation and vasoconstriction of peripheral capillaries in cold environments.
In 1930, he founded the [[Medical Research Society]]. He was awarded the Royal Society's [[Copley Medal]] in 1941 "for his clinical and experimental investigations upon the mammalian heart." He was only the second clinician to receive it, after [[Lord Lister]] in 1902. He served as vice-president of the Royal Society from 1943 to 1945.
Lewis suffered a [[myocardial infarction]] at the age of 45 and gave up his 70-cigarette-a-day habit, being one of the first to realise that smoking damaged the blood vessels.<ref name="DNB" /> He died from [[coronary heart disease]] at his home at [[Loudwater, Hertfordshire]], on 17 March 1945, at age 63.
==Family==
==Publications==
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*''Clinical Electro-Cardiography'' (1913)
==
{{Commons category}}▼
* [[List of Welsh medical pioneers]]
{{Copley Medallists 1901-1950}}▼
== References ==
▲{{Use dmy dates|date=June 2014}}
===Notes===
{{Reflist|group=upper-alpha}}
▲{{Commons category}}
===Citations===
{{Reflist}}
▲{{Copley Medallists 1901-1950}}
{{Authority control}}
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[[Category:1945 deaths]]
[[Category:People from Taff's Well]]
[[Category:
[[Category:People educated at Clifton College]]
[[Category:Alumni of Cardiff University]]
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