Tasuku Honjo
Appearance
Tasuku Honjo | |
---|---|
本庶 佑 | |
Born | |
Nationality | Japanese |
Alma mater | Kyoto University |
Known for | Class switch recombination IL-4, IL-5, AID Cancer immunotherapy PD-1 |
Awards | Imperial Prize (1996) Koch Prize (2012) Order of Culture (2013) Tang Prize (2014) Kyoto Prize (2016) Alpert Prize (2017) Nobel Prize in Physiology or Medicine (2018) |
Scientific career | |
Fields | Molecular Immunology |
Institutions | Kyoto University |
Doctoral advisor | Yasutomi Nishizuka Osamu Hayaishi |
Tasuku Honjo (本庶 佑, Honjo Tasuku, born January 27, 1942) is a Japanese immunologist. He is best known for his work of finding and naming the Programmed Cell Death Protein 1 (PD-1).[1] He is also known for his discovery of cytokines: IL-4 and IL-5,[2] as well as the discovery of Activation-induced Cytidine Deaminase (AID).[3]
He was elected as a foreign associate of the National Academy of Sciences in 2001. He is a member of German Academy of Natural Scientists Leopoldina (2003), and also as a member of the Japan Academy (2005).
In 2018, he was awarded the Nobel Prize in Physiology or Medicine along with James P. Allison.[4]
References
- ↑ Ishida, Y.; Agata, Y.; Shibahara, K.; Honjo, T. (1992). "Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death". The EMBO Journal. 11 (11). Wiley: 3887–3895. doi:10.1002/j.1460-2075.1992.tb05481.x. ISSN 0261-4189. PMC 556898. PMID 1396582.
- ↑ Kumanogoh, Atsushi; Ogata, Masato (2010-03-25). "The study of cytokines by Japanese researchers: a historical perspective". International Immunology. 22 (5): 341–345. doi:10.1093/intimm/dxq022. ISSN 0953-8178. PMID 20338911. Retrieved 2018-10-01.
- ↑ "Robert Koch Foundation confers award on Professors Honjo and Wimmer". Archived from the original on 2021-05-21. Retrieved 2018-10-02.
- ↑ Hannah, Devlin (October 2018). "James P Allison and Tasuku Honjo win Nobel prize for medicine". The Guardian. Retrieved 1 October 2018.