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The Doctor and his previous incarnations are brought to the Death Zone on his homeworld Gallifrey as part of a renegade Time Lord's scheme.

The Tardis lands in a spaceship graveyard on the bleak planet Karn, where The Doctor and Sarah find a evil scientist called Doctor Solon is constructing a new body for the brain of an evil Time Lord known as Morbius, who The Doctor thought was executed by the High Council on Gallifrey. Morbius plots to rule the galaxy with his new body.

The Tardis materializes aboard a mining ship on a desert planet, inhabited by a human crew and their robot servants. While Leela adjusts to life travelling with the Doctor, one of the ship's robots mysteriously kills a member of the crew.

Two schoolteachers investigate the personal life of one of their brilliant students and her mysterious grandfather.

On Gallifrey, someone on the High Council of the Time Lords is perpetrating a treasonous act - transmitting the Doctor's bio-extract data from the space/time Matrix to a mysterious anti-matter being they are in contact with. On Earth, two lads backpacking in Amsterdam spend the night sleeping in a crypt where they're attacked by an alien creature under the same anti-matter being's control.

The Cybermen plan on destroying Earth in order to prevent the destruction of their home world, Mondas. The Doctor also discovers the Cyber Controller is far from dead.

Knights from a parallel universe arrive on Earth to find the legendary sword Excalibur. Only the Doctor and Ace with the assistance of Brigadier Lethbridge Stewart can save the Earth from total catastrophe.

The TARDIS arrives in England, 1925, near to where a mysterious, gurgling man has escaped his bonds and started strangling servants. The Doctor is "expected" and taken (along with Tegan, Nyssa, and Adric) to the Cranleighs' country estate where The Doctor participates in a cricket match and Nyssa turns out to be the near spitting image of Ann, fiancée of Charles Cranleigh. They all stay for an afternoon costume ball. Tegan teaches others how to do the Charleston while Adric eats, but The Doctor finds himself searching through secret passageways in his bathrobe after the gurgling man steals his clothing and party costume to attend the ball and deal with one of the guests.

The Doctor attempts to test his new dematerialisation circuit by taking Jo to Metebelis Three but instead the TARDIS arrives in the hold of a 1920s cargo ship.

The Doctor has regenerated but it hasn't gone well. He's mentally unraveling and needs a place to rest beyond outside influences. Unfortunately the Master has laid a trap for the TARDIS that denies the Doctor undisturbed recovery time.

While sightseeing in Paris, the Doctor and Romana find themselves repeatedly reliving the same moments in time. A visit to the Louvre Museum leads the Doctor to suspect an alien plot to steal the Mona Lisa.

The Time Lords take control of the TARDIS and the Doctor and Jo arrive on an Earth Colony in the 25th Century, where a ruthless mining company is using a dinosaur-like creature to force the colonists to leave the planet. The Doctor and Jo learn that The Master is on the planet and is in search of a doomsday weapon that is hidden somewhere on the planet.

When someone tries to assassinate diplomat Sir Reginald Styles, UNIT investigate the possibility his attacker came from the future.

As the TARDIS heads to the paradise planet Florana where the Doctor and Sarah go for a holiday, the TARDIS goes off-course and arrives on the barren planet Exxilon, where the TARDIS is losing power. The Doctor and Sarah finds a group of humans and Daleks are searching for parrinium, a mineral which is the only antidote to a space plague. Both parties encounter the native people and trouble ensues. In an attempt to find what caused the power loss, the Doctor, chased by the Daleks, enters the Exxilon's lost city to stop the power-draining phenomenon.

The Bannermen have successfully wiped out all but the last of the Chimeron - Delta, the queen, no less. She escapes with an egg and boards an intergalactic bus of Navarino vacationers heading for 1959 Earth to visit Disneyland. On that bus is Mel, followed closely by the Doctor in his TARDIS.

The Doctor and Romana find themselves on Skaro and forced to be military advisers to the Daleks' enemy, Movellans, while the Daleks revive Davros.

In Iceworld, a trading port on the dark side of planet Svartos, the Doctor chances across Sabalom Glitz and joins him on a treasure hunt in the frozen caverns of the planet where a dragon is rumored to resides. Meanwhile Mel and a recently fired waitress named Ace run afoul of Kane, the icy director of Iceworld, whose frozen touch means death.

In the midst of an argument between Adric and the Doctor, the Tardis materializes underground in Earth's distant future where a team of paleontologists and geologists find themselves under attack from a pair of androids.

The Doctor is in a race with the clairvoyant Eternals for the prize. When the Black Guardian appears, though, the Doctor is suddenly in a race for his life!

Instead of Heathrow Airport, the Tardis lands aboard a spaceship. The Doctor and his companions meet it's inhabitants, three Urbankans, and more surprisingly a group of humans of different nationalities and from different time periods.

The Doctor and Jo discover the Master and the Ogrons are the masterminds behind the Galactic war between the Earth Federation and the Reptilian Draconian Empire. The Master has framed the Doctor and Jo as spies working for the Draconians. The Master is also working with the Doctor's greatest enemies, the Daleks, who are also behind the galactic war.

In the far flung future, the TARDIS is forced to crash land on the planet Frontios, where the Doctor finds some of the last surviving human beings cowering from a meteorite bombardment.

After receiving a summons from the Time Lords, the Doctor and Romana set course for Gallifrey, however the pair instead land on Alzarius where they cross paths with a rebellious but mathematically gifted boy named Adric.

The Doctor, Jamie and Victoria are taken prisoner by the staff of a gas refinery, who have lost contact with their drilling rigs and experienced mysterious drops in pressure.

After an encounter with a hostile robot called a Chumblie, the Doctor and his companions are rescued by a group of female Drahvins.