This is not the first time Mulder is seen wearing glasses. In Pilot (1993), Mulder is down in his office and has glasses on, plus a pocket protector. However, those were myopia glasses, while now he's wearing presbyopia ones, which mark the passage of time and how he's grown older.
Mulder asks if Scully got a haircut, and Scully responds, "are you kidding me?!" Scully's hair had been cut into the classic bob in Rm9sbG93ZXJz (2018) and Familiar (2018), but Mulder just now noticed.
Barbara Beaumont's name is a combination of Barbara Billingsley and Hugh Beaumont, who played June and Ward Cleaver on Leave It to Beaver (1957).
The glasses Mulder wears in this episode are the same glasses that Gillian Anderson wears. Gillian Anderson tweeted a photo of the glasses captioned with, "Wait...didn't I see a blonde wearing those in the back of the church?"
As of 2021, this is the final "monster of the week" story in the X-Files.