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Map of the module: Whats in a Medicine?
This shows the relationship between the Chemical Storylines, the Activities and the Chemical Ideas. To aid planning, laboratory-based practical work is indicated by (P), activities involving IT
skills are indicated by (IT) and those developing study skills by (S).
Chemical Ideas references in italics are covered in earlier modules and are included in synoptic learning outcomes for this module in the specications. Emphasis in teaching and learning
should be on the new (non-italicised) sections of Chemical Ideas. The degree to which revisited Chemical Ideas are studied will depend on the needs of individual students.
ACTIVITIES
CHEMICAL STORYLINE
CHEMICAL IDEAS
WM1 THE DEVELOPMENT OF MODERN IDEAS ABOUT
MEDICINES
WM2.1 Extraction of an active chemical from willow bark (P)
WM2.2 Nucleophilic addition reaction mechanism
WM2 MEDICINES FROM NATURE
13.2
13.7
Alcohols and ethers
Aldehydes and ketones
Salters Advanced Chemistry, Pearson Education Ltd 2009. University of York.
This document may have been altered from the original.
WM3
Investigating the chemistry of the OH group in
phenols and carboxylic acids (P)
WM3 IDENTIFYING THE ACTIVE CHEMICAL IN WILLOW
BARK
13.3
13.4
Carboxylic acids and their derivatives
The OH group in alcohols, phenols and acids
WM4
Using spectroscopy
WM4 INSTRUMENTAL ANALYSIS
6.4
6.5
Infrared spectroscopy
Mass spectrometry (section on interpreting spectra for
compounds and fragmentation)
WM5 THE SYNTHESIS OF SALICYLIC ACID AND ASPIRIN
13.5
7.3
Esters
Chromatography (section on t.l.c.)
15.8
Which reactions have the highest atom economy?
8.1
Acidbase reactions
WM5.1 Preparation of aspirin (P)
WM5.2 Combinatorial chemistry
WM5.3 Reaction type and atom economy
WM6
An aspirin assay (P)
WM6 DELIVERING THE PRODUCT
WM7 THE MIRACULOUS MEDICINE
WM8
How are new medicines developed?
WM9.1 Organic dominoes II
WM9.2 Check your knowledge and understanding (S)
WM8 DEVELOPMENT AND SAFETY TESTING OF
MEDICINES
WM9 SUMMARY
As well as the above, synoptic learning outcomes for WM indicate that students should be able to write and recognise formulae for homologous series met in the AS course, including alkenes
(Chemical Ideas 12.2) and halogenoalkanes (Chemical Ideas 13.1).
Synoptic learning outcomes also state that students should be able to predict shapes of molecules (Chemical Ideas 3.2) and use dot-cross diagrams appropriately (Chemical Ideas 3.1)
