Fossomatic™ FC
Somatic cell counting for raw milk testing
Fossomatic™ FC performs accurate milk analysis using somatic cell counting. It is a high capacity analyser (up to
600 samples per hour) that meets the demands of farmers in need of fast and reliable payment and Dairy Herd
Improvement (DHI) results. Fossomatic™ FC is based on flow cytometry technology that counts somatic cells in
compliance with ISO/IDF and FDA/NCIMS standards.
Fossomatic™ FC somatic cell counter can be integrated with the MilkoScan FT+ to form a CombiFoss™ FT+.
Supported by a dedicated Foss IntegratorTM software, which provides a wide range of quality assurance and GLP
features. Foss Integrator shares the same interface for all CMT instruments.
Sample Parameters
Milk types: Raw milk from cow, sheep, goat and buffalo Total Somatic Cell Count
Dedicated Analytical Solutions
Precision to match your standards
Do not accept dictated instrument settings. With the Fosso-
matic FC you can decide thresholds according to local require-
ments for payment and herd improvement.
In many countries the average cell count is falling as dairy herd
health improves. This has led to even lower payment limits as
well as bonus agreements for milk with an SCC below lower
limits. With the dynamic precision system of the Fossomatic
FC you have the power to do things your way.
Improved flow of reliable,
traceable measurements
The Fossomatic FC offers unique performance with the ability
to measure up to 600 samples an hour.
This speed gives you a good, profitable flow of samples through
your laboratory, more unique features such the FMA test makes
it simple to monitor the performance of the instrument. The
FMA test allows rapid and convenient instrument standardi-
zation according to the direct cell count reference method.
Safe and effective
handling of dyes and reagents
Waste liquid is split into milk, high and low concentrated waste,
helping you to dispose of waste in a safe and effective way.
An automatic rinsing function keeps the instrument clean to
ensure optimal performance. It is quick to load reagents and
operators can avoid contact with dye using the enclosed dye
bag system.
Versatile options
With the ability to measure up to 10 million cells per mil-
limetre, you can test a range of samples from cows, goats,
sheep or buffalo.
The Fossomatic™ somatic cell counter can be integrated with
the MilkoScan™ FT + to form a CombiFoss™ FT+.
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Technology
Accurate somatic cell analysis with flow cytometry
The measuring principle is flow cytometry which complies with
IDF and FDA/NCIMS requirements for somatic cell counting.
Flow Cytometry is a technique used for counting and charac-
terization of particles and cells. It can be directly translated as
“the measurement of cells while they are flowing”.
Patented dynamic precision
Until the late 1990’s all somatic cell counting (SCC) equip-
ment had been pre-set to count on the same fixed amount
of milk sample, typically from 1 µl up to 10 µl (depending on
the instrument).
Naturally, the smaller the milk sample counted, the larger the Precision Set-up
statistical errors in the result. Poisson-statistics can be applied to The Precision Set-up software feature allows the Fossomatic™
the counting of milk cells, i.e. the larger the sample, the better to run milk samples at a higher precision in certain areas, for
the precision, as described by the rule of repeatability: relative example around grading limits, without significant loss of
repeatability [in percent] =100/square root of counted cells. capacity.
The average SCC of two or more measurements is more ac-
curate than a single measurement, but performing two meas- The Precision Set-up offers three options:
urements on the same sample means doubling the analysis • Standard precision set-up
time. That is where dynamic precision comes in. • Fixed Repeatability
• Dynamic Repeatability
If you take a large portion of stained milk cells and keep
analysing this for an extended period, the results will give an Standard Precision Set-up
increasingly accurate average cell count and a better precision This set-up refers to the default way of analysing. The working
as the analysis progresses. If after 2 seconds, 3,3 µl have been factor is fixed, giving a better coefficient of Variation (CV), as
analysed, 6,6 µl will have been analysed after 4 seconds, and the SCC gets higher.
so on. But how do you find out when to stop?
Fixed Repeatability
With a fast computer you can calculate the SCC as often as
necessary and to stop the analysis as soon as the result has This set-up is used if a better repeatability (lower CV) is needed
reached the required precision. In this way dynamic precision in the low SCC area. All samples analysed in the SCC area
satisfies the requirements for both accuracy and speed in where the CV is kept fixed, are measured at a lower working
somatic cell counting. factor than in the Standard Set-up, and therefore time per
analysis increases.
Working Factor (WF) Dynamic Repeatability
The working factor refers to the volume of milk sample When selecting Dynamic Repeatability, it is possible to define
in which the somatic cells are counted. up to three SCC areas, with a higher precision (lower working
factor) than offered by the Standard Set-up. This is used to
Repeatability
give an even better precision around grading limits.
The repeatability (CV) expresses to which degree the ana-
lyser is capable of counting the same amount of somatic
cells in the same milk sample.
The higher the SCC, the better the CV. The lower the WF,
the better the CV.
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How Fossomatic™ FC works
The Fossomatic FC counts somatic cells based on recognition of DNA from the cells.
A mixture of milk and staining solution is surrounded by a sheath liquid and passed through a
flow cell. In the flow cell, the stained somatic cells are exposed to light of a specific wavelength.
The cells then emit fluorescent light pulses at a different wavelength, the pulses are counted
and displayed.
The design of the flow cell ensures that only one somatic cell is detected at a time. Higher preci-
sion can be obtained at grading limits using precision set-up feature.
Universal software
The Windows-based Foss Integrator software platform eases
operations. A PHA diagram helps the operator make a fast
and accurate evaluation. Radio Frequency ID (RFID) tags pro-
vide modern sample identification. Automatic Job Control
helps reduce the operator workload. Perform calculations on
results in your own Excel spreadsheet, and return data to the
Integrator platform.
Reagent concept
All Fossomatic reagents are certified, an important feature
for laboratories operating according to ISO /IEC 17025:2005,
and are handled in a closed system that protects the operator.
Quality assurance Waste is split into fractions to reduce the cost of waste disposal.
The Fossomatic™ Adjustment Sample (FMA) and the Qual-
ity Check Application is a combination of applied chemistry
and computer software that allows detailed monitoring of
Fossomatic performance. Well-defined artificial particles in a
liquid suspension can be stained and measured just like so
matic cells in milk, allowing you to adjust the instrument for
optimum performance.
With the FMA Sample and Fossomatic Quality Check Applica-
tion you get:
• Easy routine instrument check
• Performance documentation
• Early detection of potential measurement problems
• Suggested corrective actions
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Best of the new
To match the increasing demands of the modern laboratory
Fossomatic FC includes a number of new features that optimise
laboratory efficiency and keep costs down:
• Higher speed, up to 600 samples per hour
• Improved rinse system prevents blockage and reduces down-
time
• Improved reliability/accessibility of flow system parts - keeps
maintenance down
• All liquids are temperature-controlled to optimise the staining
and cleaning
• Universal software platform (Foss Integrator) with improved
data handling and integrated help system makes it easy to
handle all FOSS CMT analysers
• Not only for cow’s milk, also milk from other species such
as sheep and goats
Conveyor system with in-built Sample ID CombiFoss™
You have a choice of a few automation solutions for the FOSS The Fossomatic™ FC can be integrated with a MilkoScan
analysers to match your needs best. Two impressive, and highly FT+ multi-component analyser to form a CombiFoss™ FT+,
appreciated by our customers, standard conveyor systems are without reducing sample capacity and at the same time pro-
available: Conveyor 4000 and Conveyor Basic. They are intel- moting operational effectiveness by sharing the Foss Integrator
ligent units with a built-in microprocessor, controlled by the software platform.
analyser and providing at minimum:
• Rack advance and positioning of sample bottles under the
stirrer and pipette
• Sample identification for the “ladder” position of the bar
codes*
• Automatic detection of check-samples
Conveyor 4000 is the advanced and most flexible solution
with many additional useful functions like:
• Automatic rewind of racks with samples to be re-tested
• Sample identification for bar codes of all positions, as well
as 2D and RF-tags*
• Unique bottle rotation mechanism, for fully automated
sample identification*
• Sample temperature conservation Fossomatic FC in a CombiFoss™ configuration
• Extensions for creating more space for the bottle racks*
• Sample buffering*
The Fossomatic™ FC gives you the analysis performance you
A semi-automatic option ideal for milk-testing laboratories with need to meet new demands for analysis efficiency, and it of-
a lower sample throughput is also available. In this version, a fers you exciting new business opportunities at the leading
plate is placed instead of the conveyor. edge of milk analysis.
*Optional
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Specifications
Performance
Measuring range 0 – 10 mill cells/ml
Performance range 0.1 – 1.5 mill
CV < 6% 100-299k SCC/ml
Repeatability* CV < 4% 300-499k SCC/ml
CV < 3% 500-1500k SCC/ml
CV < 3.5% 100-299k SCC/ml
Repeatability with
CV < 2.5% 300-499k SCC/ml
precision setup in use
CV < 2% 500-1500k SCC/ml
Accuracy < 10% relative mean diff. from DMSCC
(Direct Microscopic Somatic Cell Count)
Carry-over < 1% relative usually below 0.4%
Sample types Cow’s, goat’s, sheep’s milk and other
*CV = Coefficient of variation (STDev/AVG) x 100. (STDev = Standard deviation. AVG = Average)
Installation requirements Fossomatic FC Conveyor
Dimensions (HxWxD) 63 x 85 x 68 cm 72-95 x 230 x 28 cm
Weight 100 kg 57 kg
Power supply 100 - 240 VAC, 50/60 Hz 115/230 VAC, 50/60 Hz
Power consumption Max. 800 VA Max. 500 VA
Compressed air None 4.0 – 7.2 bar
Air consumption - 0.2 N litre per minute
Ambient temperature 15 - 33°C 15 - 33°C
Noise level < 70 dB(A)
Application data
Analysis Capacity* 100, 200, 300, 400, 500 or 600 samples per hour
Sample intake 2.5 ml (programmable 2.0 – 5.0 ml)
Required sample temperature 30 - 42 °C (86-107.6 F)
Working factor 300 or better
*The Fossomatic FC is also available in a semiautomatic version without automatic sample conveyor.
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Data output
Real-time display/print-out, storage on hard disk.
Host transmission (RS232) and PC network transmission (TCP/IP).
Data export using CSV files, CS83 protocol or XML.
Standard equipment
Basic analyser incl. table and reagent containers, PC, software.
Optional equipment
Conveyor 4000 or Conveyor Basic, extra containers for reagents, bar code readers, 2D reader, RFID reader, system for sample
bottle rotation, extensions for the Conveyor 4000, bottle rack output buffer for the Conveyor 4000, racks for sample bottles,
printer.
Standards and approvals
Fossomatic™ FC is CE-labelled and complies with the following directives and regulations:
• EMC (ElectroMagnetic Compatibility) Directive 2004/108/EC
• LVD (Low Voltage) Directive 2006/95/EC
• Machinery Safety Directive 2006/42/EC
• Regulation (EC) 1272/2008 on classification, labelling and packaging of substances and mixture, CLP (EC)
• WEEE Directive 2002/96/EC
• Packaging and packaging waste Directive 94/62/EC
• REACH 1907/2006/EC
Fossomatic technology complies with:
• AOAC
• ISO 13366-2 / IDF 148-2:2006
• Laser approval (FDA), IEC 60825-1
P/N 1026668, Issue 2, GB, October 2015
FOSS
Foss Allé 1
DK-3400 Hilleroed
Denmark
Tel.: +45 7010 3370
Fax: +45 7010 3371
info@[Link]
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