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Medication Risks: Ototoxicity, Hepatotoxicity, Nephrotoxicity

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140 views1 page

Medication Risks: Ototoxicity, Hepatotoxicity, Nephrotoxicity

Uploaded by

IFLXECRT
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

MEDICATION RISKS

NOTES
Bad for Ears (Ototoxicity)
Antibiotics
z Gentamicin and tobramycin
z Macrolides (reversible)

Loop diuretics
z Furosemide

Chemotherapy
z Cisplatin
z Carboplatin

Bad for Liver (Hepatotoxicity)

Elevated liver enzymes (ALT, AST) Antihypertensives Pain


Normal: z ACE inhibitors z Acetaminophen
z ALT: 7 - 46 units/L z NSAIDs
z AST: 10-40 units/L Anti-infectives
z Erythromycin Tuberculosis
z Fluconazole z Rifampin
Unusual fatigue/weakness, loss of z INH
z Itraconazole
appetite, pain in upper abdomen, dark-
colored urine, yellowing of skin or eyes Alcohol Psych
z Phenothiazines

WATCH FOR:
Bad for Kidneys (Nephrotoxicity)
Radiocontrast media Elevated BUN
(especially with Normal:
Antibiotics
metformin) z 7 - 20 mg/dL (2.5 - 7.1 mmol/L)
z Gentamicin
z Amphotericin B Lithium salts
z Rifampin Elevated serum creatinine
ACE inhibitors Normal:
z INH
NSAIDs z Women: 0.6 - 1.1 mg/dL
Chemotherapy z Men: 0.7 - 1.3 mg/dL
z Cisplatin

www.lecturio.com/nursing WATCH VIDEO

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