DRUGS OF ABUSE
Drug Testing - increasing
applicability
• government agencies
• industrial agencies
• sports agencies
Forensic Drug Testing
- the application of
drug testing to questions of law
ACTIVITY # 21
DRUG TESTING: MET & THC
Tetrahydrocannabinol
Methamphetamine
Peak effect: 20-30
Last about 2-4
mins
hours
Duration: 90-120 mins
Half-life: 9-24 hours
Derivatives in urine: 3
10-20% is excreted
to 5 days after
in urine
smoking
Detected: 3-5 days
Derivative in urine: Δ9-
Cut-off Value: 1,000 THC-COOH
ng/mL
Cut-off Value: 50 ng/mL
TEST PRINCIPLE
Competition for antibody binding
between drug-protein conjugates
and drugs that may be present in
the urine sample.
Band regions: drug-protein
conjugates
Gold Pad: mouse monoclonal Ab
conjugated with gold particles
Ab on the test strip allows for
selective ID of THC and MET
SPECIMEN
COLLECTION
PROCEDURE
RESULTS
RESULTS