Total No. of Questions : 3] SEAT No.
P937 [Total No. of Pages : 2
[5854]-4001
S.Y.B. Pharmacy
PHARMACEUTICAL ORGANIC CHEMISTRY - III
(2019 Pattern) (Semester - IV) (BP401T)
Time : 3 Hours] [Max. Marks : 75
Instructions to the candidates:
1) All questions are compulsory.
2) Write reactions wherever necessary.
3) Figures to the right indicate full marks.
Q1) Objective Type Questions Any 5 out of 7 : [5 3 = 15]
a) Chair conformation of cyclohexane is more stable than boat conformation.
Why?
b) Give any three reactions of thiophene.
c) Draw the following heterocycles with numbering.
i) Pyrimidine ii) Oxazole iii) Benzimidazole
d) Write Synthesis of Furan.
e) Discuss principal behind oppenauer-oxidation.
f) Give any three reactions of quinoline.
g) Describe Hansch synthesis of pyridine with Mechanism.
Q2) Long Answer Any 2 out of 4 : [2 10 = 20]
a) What is meant by racemic modification. Explain various methods of reso-
lution of racemic mixture.
b) Give methods of synthesis & reactions of pyrrole.
c) Discuss reaction, mechanism & applications of Benzilic acid rearrange-
ment & Pinacol-Pinacolone rearrangement reaction.
d) Elaborate method of synthesis, reactions & medicinal uses of Imidazole.
P.T.O.
Q3) Short Answer Any 8 out of 10 : [8 5 = 40]
a) Write a note on Atropisomerism.
b) What are stereospecific & stero selective reaction.
c) Comment on conformational isomerism in n-butane.
d) Asymmetric synthesis.
e) Discuss mechanism involved in Claisen-Schmidt condensation.
f) Explain the mechanism reaction conditions & industrial applications of
Fischer indole synthesis.
g) Outline two methods of synthesis & chemical reactions of Thiazole.
h) Discuss synthesis & medicinal uses of Purine.
i) What is clemmensen reduction? Give its application.
j) Explain in detail Birch reduction.
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