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Applied Pharmacology 35 Hrs

SECTI ON B Q P CODE: 5134

Syllabus Total teaching - 35hrs

1. Introduction a. Definition and tenninology

Pharmacology, Drug (WHO Definition),
Pharmacokinetics, pharmacodynamics,
Pharmacotherapeutics, chemotherapy, chemoprophylaxis,
Clinical pharmacology, Toxicology and Pharmacopeias.
b. Drug nomenclature, prototype drug.
c. Concept of essential Medicines list
d. Sources of drugs.
2. Dosage fonns of drugs-types with examples
l.
3. Routes of drug administration in general and emphasis on intravenous (IV), IM
and inhalational route of administration of drugs
4. Adverse drug reactions (ADR), Definition and types, with emphasis on side
effects, hypersensitivity reactions· and their management.
5. Analgesics - Definition and types,
Commonly used NSAIDS- their uses, adverse effects &
precautions
Aspirin, Ibuprofen, Diclofenac, Aceclofenac, ketorolac,
paracetamo1
Opioids - Morphine, Pethidine, Pentazocine, Fentanyl
Alfentanil, Sufentanil and Ramifentanil
Uses, adverse effects, precautions & contraindications.
6. Sedatives hypnotics- Definition, uses, adverse effects of diazepam, lorazepam
and midazolam.
7. Local anesthetics - Definition, classification and in detail of commonly used
drugs like Lignocaine, bupivacaine, eutectic. mixture,
Techniques of LA
8. General anaesthetics
Halothane, Isoflurane, Sevoflurane, Thiopentone sodium, Propofol,
Ketamine and pre- anaesthetic medication
9. Corticosteroids- definition, classification, uses, adverse effects and
contraindications and emphasis on hydrocortisone
10. Antiseptics and disinfectants -commonly used drugs in OT, OT fumigation
 11. Skeletal muscle relaxants-- uses, adverse effects and contraindications of
succinyl choline, Pancuronium, Vecuronium,
Rocuronium and Mivacurium
12. Anti-emetics metoclopramide, ondansetron
13. Intravenous fl~ids -- crystalloids and colloids
14. Emergency drugs used in OT
• Atropine
• Adrenaline
• Nor-adrenaline
• Dopamine· & Dobutamine
• Chlorpheneramine maleate
• Pro1nethazine
• Vasopressin
• Deriphyllin &Aminophylline
• Frusemide and fyfannitol
• Sodium bicarbonate
• Hydrocartisone & dexamethasone
• Mephenteramine
• Esmolol, labetalol
• Verapamil, amiodarone, lignocaine
• Diazepam, lorazepam
• Sodium nitroprusside, nitroglycerine
• Anti-fibrinolytics
• Styptics
• Emphasis on management of Medical/ surgical emergencies-anaphylactic shock,
hypotension, seizure~, acute adrenal crisis, acute asthma, haemorrhage &
hypovolemia, arrhythmias, .hypoglycemia, hypertensive crisis

15. Drugs used in acid peptic disorders -ranitidine and pantoprazole

• 16. Drugs used in m~nag~ment of hypertension-commonly use_d drugs
18._ Drugs used in management of Diabetes mellitus- Insulin - Uses & Adverse
effects and Precautions during use.
19. Antimicrobial drugs - General considerations, Beta-Lactam antibiotics
Fluoroquinolones and aminoglycosides
Metronidazole
Antiretroviral drugs used in post exposure prophylaxis
 MICROBIOLOGY 20 Hrs

SECTION C Q P CODE: 5135

Introduction and History of Microbiology 5 marks

Lewis Pasteur, Robert Koch, Lister, Edward Jenner, Nonnal Flora of
skin/ body

Sterilization and disinfection: 10 marks

Dry and moist heat of sterilization
Sterilization of mask, endotracheal tube
Respitator / OT sterilization I Other equipment

Bacteriology- Classification, Morphology of Bacteria 5 marks

Immunity- Active, Passive, Hypersensitivity (Immunisation)
Reaction of the body - local, specific effects to certain organism

• Common diseases caused by different types of organisms

Staph, Strepto, C. tetanus, and welchii, Mycobacterium tuberculosis,
[Link], Pseudomonas (Candida crypotcoccus)
Virology- Hepatitis (HBV, HCV), HIV, etc.
10 marks

Nosocomial infections & infection control measures

Universal precautions
Bio Medical Waste Disposal

NO PRACTICAL EXAMINATION IN MICROBIOLOGY