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Hormones and Enzymes Overview

This diagram outlines the key steps in steroid hormone synthesis in the body. Cholesterol is converted to pregnenolone by the enzyme StAR, and pregnenolone can then be converted through a series of hydroxylation and lyase reactions into other steroid hormones like cortisol, aldosterone, testosterone, estrogen, progesterone and DHEA. These steroid hormones are important regulators of physiology and metabolism.

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Krairat Komdee
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50 views1 page

Hormones and Enzymes Overview

This diagram outlines the key steps in steroid hormone synthesis in the body. Cholesterol is converted to pregnenolone by the enzyme StAR, and pregnenolone can then be converted through a series of hydroxylation and lyase reactions into other steroid hormones like cortisol, aldosterone, testosterone, estrogen, progesterone and DHEA. These steroid hormones are important regulators of physiology and metabolism.

Uploaded by

Krairat Komdee
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd

Cholestero

l
StAR, 20,22desmolase
17Pregnenolon
hydroxylase17-OH-

17,20-lyase

DHEA

Pregnenolone
3HSD
3HS
D
17Progesteron
hydroxylase17-OHe

21hydroxylase

DOC

11hydroxylase

Corticostero
ne

18-hydroxylase

18-OHCorticosterone
18-oxidase

Aldostero
ne

17,20-lyase

Progesterone
21hydroxylase

11deoxycortisol
11-hydroxylase

Cortiso
l

3HS
D

Androstenedio
aromatase
ne
17HSD

Estrone
Testosteron
e
aromatase

17HSD

Estradiol

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