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Parkinson's & Movement disorders news
New study reveals promising therapy that blocks microRNAs to treat myotonic dystrophy type 1
A team of researchers has identified a promising therapy based on antimiRs to treat myotonic dystrophy type 1 (DM1), a complex genetic disorder caused by an abnormally high number of CTG repeats (a specific type of RNA sequence) ...
Oct 15, 2024
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Toxic protein may contribute to amyotrophic lateral sclerosis development
A toxic version of a certain protein may affect brain, spinal cord and skeletal muscle tissues differently, leading to the complex development and progression of amyotrophic lateral sclerosis (ALS), according to a new study ...
Oct 14, 2024
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Researchers create 'mini brains' to model Lewy body dementia and pinpoint treatments
Lewy body dementia (LBD) is a progressive neurodegenerative disease that shares traits with both Parkinson's disease and Alzheimer's disease but can be more difficult to diagnose. Symptoms can include hallucinations, movement ...
Oct 14, 2024
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Clinical trial finds multidisciplinary approach improves quality of life for movement disorder patients
A research team has published a randomized clinical trial demonstrating for the first time that a multidisciplinary approach integrating specific physiotherapy and cognitive-behavioral therapy is effective in improving the ...
Oct 11, 2024
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Scientists use stem cells to recreate a hallmark of Parkinson's disease in human neurons
Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.
Oct 8, 2024
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Brain molecule reverses movement deficits of Parkinson's, offering new therapeutic target
A research team from the University of California, Irvine is the first to reveal that a molecule in the brain—ophthalmic acid—unexpectedly acts like a neurotransmitter similar to dopamine in regulating motor function, ...
Oct 4, 2024
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Visual mismatch negativity identified as a mechanism of Parkinson's disease psychosis
Reduced brain activity responding to unpredicted visual changes is a marker of psychosis in Parkinson's disease and a potential therapeutic target. Researchers at the IoPPN used electroencephalography (EEG) to observe participant's ...
Oct 1, 2024
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Automatic speech recognition learns to understand people with Parkinson's disease—by listening to them
As Mark Hasegawa-Johnson combed through data from his latest project, he was pleasantly surprised to uncover a recipe for Eggs Florentine. Sifting through hundreds of hours of recorded speech will unearth a treasure or two, ...
Sep 27, 2024
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How a Colorado Parkinson's group uses climbing to help stave off effects of the disease
For 12 years, Paul Stroud's done everything he can to combat the effects of Parkinson's disease. He had a pair of stimulators implanted deep in his brain. He takes the standard medications to treat symptoms. He even briefly ...
Sep 27, 2024
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Scientists discover mutation linked to early-onset Parkinsonism
A team of scientists led by Prof. Patrik Verstreken (VIB-KU Leuven) has identified a new genetic mutation that may cause a form of early-onset Parkinsonism. The research has been published in Cell Reports Medicine.
Sep 26, 2024
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Unlocking the energy crisis in Parkinson's: New findings on metabolic disruptions
Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.
Sep 26, 2024
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Right-side deep brain stimulation may preserve verbal fluency in Parkinson's patients
Deep brain stimulation is an effective treatment for motor symptoms in patients with movement disorders such as Parkinson's disease. While ultimately regarded as safe, DBS can yield noticeable declines in verbal fluency, ...
Sep 26, 2024
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Researchers create mouse model to mimic Parkinson's disease
Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease research and modeling. ...
Sep 25, 2024
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A risky business: Why do some Parkinson's disease treatments affect decision making?
Parkinson's disease (PD), also known simply as Parkinson's, is a disorder of the nervous system that affects millions of people worldwide. The nerve cell damage associated with Parkinson's can cause tremors, slowed movements, ...
Sep 24, 2024
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Q&A: New tech could improve care for Parkinson's patients
The number of people living with Parkinson's disease globally has doubled in the past 25 years. Yet the treatment and monitoring of the neurological disease seems many decades behind. Clinicians typically gauge the severity ...
Sep 24, 2024
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Wearable sensors, machine learning system could pinpoint Parkinson's
Parkinson's comes on slowly, and diagnosing the often-devastating movement disorder, particularly in its early stages, usually entails having patients perform a variety of mobility tasks, observing their walking and movement ...
Sep 23, 2024
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Study finds brain intervenes in walking only after discoordination exceeds a certain threshold
Walking is an activity that is often taken for granted. Most people usually think they can multitask by "walking and chewing gum" simultaneously with hardly any taxation of their mental effort. Indeed, each leg can move rhythmically ...
Sep 20, 2024
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Air pollution exposure increases risk for Parkinson's disease
Higher exposure to air pollution increases the risk for Parkinson's disease (PD), according to a study published online Sept. 16 in JAMA Network Open.
Sep 20, 2024
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Novel drug molecule could help treat Parkinson's disease in young patients
More than 100,000 Canadians currently live with Parkinson's disease. A novel drug molecule being studied by researchers from McGill University could reactivate housekeeping functions in brain cells of young Parkinson's patients, ...
Sep 19, 2024
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Some diabetes drugs tied to lower risk of dementia, Parkinson's disease
A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a study published in the September 18, 2024, online issue of Neurology.
Sep 18, 2024
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Innovative technology may enable early diagnosis of Parkinson's disease
Researchers at Tel Aviv University cooperated with three major Israeli medical centers to develop a new method for detecting protein aggregation in cells—a hallmark of Parkinson's disease. The technology can enable diagnosis ...
Sep 16, 2024
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Genetics suggest link between ALS and Parkinson's disease
People with rare genetic variants linked to degenerative brain disorders like Parkinson's disease are at increased risk of developing ALS, a new study finds.
Sep 16, 2024
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Rapid blood diagnostic test developed for amyotrophic lateral sclerosis
A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that affects neurons in the brain and spinal cord.
Sep 12, 2024
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