Optineurin dysfunction-induced neurodegeneration. A role for microtubule-dependent mitochondrial transport: prospective for neuroprotection and, possibly, regeneration. #neurodegeneration #GeneTherapyResearch #NeuroDiseases #Neuro #ALS #neurogenesis #genetics #geneediting #neuroprotection #iPSCs #regenerativemedicine #neuroregeneration #axonopathy #mitochondria #axonaltransport #optineurin Yang Hu https://lnkd.in/dJKgAZXH
Neuroscience School of Advanced Studies
Higher Education
London, England 2,502 followers
Advanced Courses, Workshops and Summits with the world leaders of neuroscience
About us
The Neuroscience School of Advanced Studies, using a unique format of high-impact learning experiences, takes neuroscientists of all levels outside the comfort zone of their own expertise, empowering them with new analytical and strategic skills across basic and clinical neuroscience. Learning from the absolute thought leaders provides neuroscientists with a tremendous reserve of strategic thinking to be put to immediate use as well as mobilized as contingencies demand. Based in London, UK, the NSAS hosts different study sessions in international venues specifically chosen for their exceptional scenery, including the Swiss Alps, the Côte d'Azur and Venice.
- Website
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www.neurosas.org
External link for Neuroscience School of Advanced Studies
- Industry
- Higher Education
- Company size
- 2-10 employees
- Headquarters
- London, England
- Type
- Educational
- Founded
- 2010
- Specialties
- Neuroscience, Biomedical Education, Neurotechnology, Neurology, Psychiatry, Brain Research
Locations
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Primary
118 Pall Mall
London, England SW1Y 5EA, GB
Employees at Neuroscience School of Advanced Studies
Updates
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Analysis of human cerebral organoids from patients with mutations mimicking periventricular heterotopia reveals increased morphological complexity of PH neurons and synaptic alterations contributing to increased spontaneous spike activity. A comprehensive study of importance for the understanding of cortical malformations and the underpinnings of the resulting epilepsy, cognitive and behavioral deficits. #neuroscience #neuroplasticity #neuralpathways #neuralnetworks #neuralcircuits #GeneTherapy #NeuroDiseases #genetics #organoids #cortex #malformation #epilepsy #cognitivedeficit #neuronalfiring #transcriptomics #proteomics Silvia Cappello https://lnkd.in/dpcAeA6c
Neuronal hyperactivity in neurons derived from individuals with gray matter heterotopia - Nature Communications
nature.com
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POMC neurons projecting to the paraventricular thalamus regulate the preference for sweet food after the consumption of a standard meal in rodents. Towards the identification of a neural circuit for the "dessert stomach"? #foodintake #POMC #hypothalamus #thalamus #mureceptors #opioids #arcuatenucleus #satiety #neuralcircuits Henning Fenselau https://lnkd.in/ed9C2zWm
Thalamic opioids from POMC satiety neurons switch on sugar appetite
science.org
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Brain-wide imaging of immediate early genes followed by machine learning as a novel classification tool for psychedelics and other psychoactive drugs. #psychedelics #psychoactivedrugs #immediateearlygenes #cFOS #brainimaging #psilocybin #ketamine #5MeODMT #MDMA #fluoxetine #5HT2a #serotonin Alex Kwan https://lnkd.in/d4dEEaxm
Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression - Nature Communications
nature.com
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Just out. Striatal neuron vulnerability in Huntington's Disease may be explained by accelerated epigenetic aging. Focus on de-repression of developmental genes. A very interesting perspective. #HD #Huntington #epigenetic #neuroepigenetic #striatum #neurodegeneration #aging #neurodevelopment #neurogenetics #gene #stressresponse #homeostasis #HTT #Huntingtin #spinyneurons #CAG Karine Merienne https://lnkd.in/dymza72K
Accelerated epigenetic aging in Huntington’s disease involves polycomb repressive complex 1 - Nature Communications
nature.com
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Chronic back pain: Targeting new proteins for pain drug development and advancing towards a personalized approach. A meta-analysis of multi-ancestry GWAS identifies genetic factors associated with chronic back pain. #pain #drugdevelopment #genetics #neurogenetics #chronicbackpain #GWAS https://lnkd.in/dCRStegA
Multi-ancestry meta-analysis of genome-wide association studies discovers 67 new loci associated with chronic back pain - Nature Communications
nature.com
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*** NIH to cut indirect costs of all grants to 15% *** Just released https://lnkd.in/eeYSAMeF
Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
grants.nih.gov
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Neurobiology of addiction: A very timely review of drug-induced plasticity at the molecular, cellular, and synaptic levels, with a translational perspective. #neuroscience #neuroplasticity #neuralpathways #neuralnetworks #neuralcircuits #addiction #drugsofabuse #cocaine #psychostimulants #glutamate #limibicsystem #nucleusaccumbens Eric J. Nestler, MD, PhD https://lnkd.in/eXEdweCk
The biology of addiction
science.org
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Neurocircuitry of the human hypothalamus. Single-nucleus RNA sequencing (snRNA-seq) and spatial transcriptomic data for a detailed spatio-cellular map. #hypothalamus #neuroscience #neuralpathways #neuralnetworks #neuralcircuits #POMC #AgRP #arcuatenucleus #RNA #RNAsequencing #transcriptomics Giles Yeo https://lnkd.in/eSFkP4Tj
A comprehensive spatio-cellular map of the human hypothalamus - Nature
nature.com
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An interesting review paper on the clinical future of organoids. Just out. #organoids #iPS #neuralstemcells #neurogenesis #geneediting #iPSCs #regenerativemedicine #neurodevelopment https://lnkd.in/dn8_9JTN
Clinical applications of human organoids - Nature Medicine
nature.com