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Scientists from Rockefeller University and Mount Sinai have unveiled a groundbreaking discovery shedding light on addiction. Their findings reveal a newly identified brain pathway that offers crucial insights into the neural processing of rewards and addictive substances. By delving into the nucleus accumbens (NAc), a key region involved in reward processing, the researchers discovered how cocaine and morphine activate specific subsets of neurons, leading to distinct behavioral outcomes compared to natural rewards. Moreover, they identified a molecular pathway involving the Rheb gene and the mTOR pathway, which may explain how addictive substances skew natural urges, such as hunger and thirst, by altering neural communication and memory. This research not only deepens our understanding of addiction but also opens new avenues for developing targeted interventions to restore the brain's natural reward processing mechanisms. Learn more: https://lnkd.in/esC6rVna #AddictionResearch #AnimalResearch #LaboratoryAnimalSciences

Newly discovered brain pathway sheds light on addiction - News

Newly discovered brain pathway sheds light on addiction - News

rockefeller.edu

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