Scientists from Rockefeller University and Mount Sinai have unveiled a groundbreaking discovery shedding light on addiction. Their findings reveal a newly identified brain pathway that offers crucial insights into the neural processing of rewards and addictive substances. By delving into the nucleus accumbens (NAc), a key region involved in reward processing, the researchers discovered how cocaine and morphine activate specific subsets of neurons, leading to distinct behavioral outcomes compared to natural rewards. Moreover, they identified a molecular pathway involving the Rheb gene and the mTOR pathway, which may explain how addictive substances skew natural urges, such as hunger and thirst, by altering neural communication and memory. This research not only deepens our understanding of addiction but also opens new avenues for developing targeted interventions to restore the brain's natural reward processing mechanisms. Learn more: https://lnkd.in/esC6rVna #AddictionResearch #AnimalResearch #LaboratoryAnimalSciences
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Precision music programming has power to pair into, and hijack addiction pathways, then retrain, re-order and reconstruct addiction pathways over a circadian/calendar structured recovery period. Precision music programming then can maintain global network stability and purest physiologic balance (in the reward /physiologic system) to enable/ensure long-term maintenance away from drug addiction. The trick is to program music that pairs with addictive rhythm and resonance, along with other considerations (cultural/music memory bank) that move in, associate with patient, and immediately work to temper drug withdrawal. This first pairs with addiction chaos (or ptsd, adhd, name condition) then gradually-methodically/systematically pulls the physiology and associated networks to normalized reward circuits. Music - precision, organized, proper and appropriate medical level music applications, then assists to maintain recovery and neurophysiological balance on a circadian prescriptive level. I’m working with data mining and health informatics medicalrecord systems to oversee implementation of real prescriptive music medical interventions that are reliable, reproducible, standardized, quantitative, and measurable, with real lasting health-based pinnacle outcomes in patients. I have tried to develop a full and working theory of precision music medicine that is understandable, reproducible, valid, definable, measurable, and gold standard applications in the medical field. The good news is that Doctors, nurses, and trained scientists understand exactly what I’m talking about. I have merged the fields of music and science and speak the language of science that is the foundation of precision music in true reliable medical-level healing.
How Drugs Hijack the Brain’s Reward System A new study unveils how cocaine & morphine disrupt the brain's reward pathways, offering new targets for addiction treatment. Discover how these drugs overpower natural rewards, leading to compulsive behavior.
How Drugs Hijack the Brain's Reward System - Neuroscience News
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On substances hijacking the brain's reward system:
How Drugs Hijack the Brain’s Reward System A new study unveils how cocaine & morphine disrupt the brain's reward pathways, offering new targets for addiction treatment. Discover how these drugs overpower natural rewards, leading to compulsive behavior.
How Drugs Hijack the Brain's Reward System - Neuroscience News
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💎💎💎Whatsapp!! 💎💎💎 Addiction + Neurons 34 Neuron Subtypes Linked to Addiction Researchers identified 34 distinct subtypes of medium spiny #neurons (MSNs) in the #nucleus accumbens, a #brain #region crucial for reward and #addiction. This discovery challenges previous views of #MSNs as a homogeneous group, revealing a complex diversity with potential implications for understanding addiction and developing targeted #therapies. The study suggests these findings may be conserved across species, offering insights into #human #brain function. 34 distinct MSN subtypes were identified, each with #unique #genetic #profiles. MSNs play a key role in reward processing and substance use #disorders. The findings could lead to more targeted and #effective #treatments for addiction. ➡ 💎 You can find more pieces of work by clicking here. https://lnkd.in/eSG67K5G https://lnkd.in/dB3s88ei #neurons #nucleus #brain #region #addiction
34 Neuron Subtypes Linked to Addiction - Neuroscience News
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Breaking Ground in Addiction Research: HPLC-ECD in Action The Hemby Lab at High Point University is making strides in substance abuse disorder research by exploring novel compounds to suppress drug self-administration. Their innovative use of HPLC-ECD analysis allows for precise detection of dopamine and serotonin, revealing the neurochemical impacts of experimental compounds. These insights could pave the way for therapeutic breakthroughs, alleviating human suffering and reducing the societal burden of addiction. Dive into the full case study to learn more about: - How HPLC-ECD simplifies neurotransmitter analysis. - Techniques for understanding addiction's neurochemical roots. - Potential therapies inspired by comprehensive research. Read the Case Study: https://lnkd.in/gudKUa2q #AddictionResearch #HPLCECD #NeuroscienceTools #TherapeuticBreakthroughs #BreakthroughWithAmuza
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SPHERE Coaching - 34 Neuron Subtypes Linked to Addiction Researchers identified 34 distinct subtypes of medium spiny neurons (MSNs) in the nucleus accumbens, a brain region crucial for reward and addiction. This discovery challenges previous views of MSNs as a homogeneous group, revealing a complex diversity with potential implications for understanding addiction and developing targeted therapies. The study suggests these findings may be conserved across species, offering insights into human brain function. #BeAbrainOwner https://vist.ly/3eipe
34 Neuron Subtypes Linked to Addiction - Neuroscience News
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India: Combined Addiction and Neurobiological Targets: An In Silico Analysis of Areca Nut and Areca Nut with Tobacco Biomolecules
Combined Addiction and Neurobiological Targets: An In Silico Analysis of Areca Nut and Areca Nut with Tobacco Biomolecules - PubMed
pubmed.ncbi.nlm.nih.gov
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🚨 New Insights on Addiction & Myelination from Stanford Medicine 🧠 Great article: Stanford researchers found that opioid addiction might be reinforced by changes in brain myelination—the process that strengthens neural circuits. A single dose of morphine triggered these changes in dopamine neurons, promoting drug-seeking behavior. Blocking myelination in these pathways halted addiction in animal models, offering new hope for treatment strategies targeting brain plasticity. This discovery opens doors for innovative approaches to addiction therapy by reversing these brain changes. https://lnkd.in/eiaT96xC Stanford University School of Medicine #AddictionRecovery #Neuroscience #MentalHealth #StanfordMedicine
Myelination in the brain may be key to ‘learning’ opioid addiction
med.stanford.edu
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I am happy to share that my newest review from my graduate studies has been accepted for publication in Addiction Neuroscience and is now available in-press. Thank you Patrick Randall and Yuval Silberman for your guidance, support, and knowledge in writing this review. This review focuses on the neuroimmune aspect of addiction, examining the role of the central amygdala neuroimmune signaling in alcohol use disorder. The review highlights how neuroimmune changes contribute to the dysregulation of neural circuits involved in reward and stress, perpetuating alcohol-seeking behavior and relapse. Through examining these neuroimmune mechanisms, we can potentially target them as a novel therapeutic approach for alcohol use disorder. You can find the article here: https://lnkd.in/e8R2vDJA
Central Amygdala Neuroimmune Signaling in Alcohol Use Disorder
sciencedirect.com
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Nova postagem: The genetics of behavior in Psychoactive Substance Use disorder: A complex approach - https://lnkd.in/dJip4NuW substance use disorder (TUS) is a complex and multifactorial condition, with causes ranging from environmental factors to genetic predispositions. The influence of genetics on the behavior of users of psychoactive substances is a field of study in constant development, with new discoveries that can help in the understanding and treatment of this condition. Silveira, […]
The genetics of behavior in Psychoactive Substance Use disorder: A complex approach
https://neurogenomic.com
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The discovery of this third dopamine pathway is like finding a missing piece in the puzzle of brain function. It explains how the brain fine-tunes motor control and cognitive balance, a crucial element in both psychiatric and neurological disorders. But here’s the question: How does this fit into real-world treatments? It’s one thing to pinpoint this small group of neurons, but can we effectively target them with therapies without creating a cascade of unintended side effects? The leap from lab to treatment will be where the magic—or the mess—really happens. #DopamineDiscovery #NeuroscienceBreakthrough #BrainFunction
Hidden Dopamine Neurons Balance Brain Functions and Behavior New research uncovers a crucial group of dopamine neurons in the brain that may unlock new treatments for disorders like Parkinson's, schizophrenia, and addiction. This breakthrough could reshape our understanding of brain function and disease.
Hidden Dopamine Neurons Balance Brain Functions and Behavior - Neuroscience News
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