New research by Dr. Karina Eterovic, MSc, PhD, NYS CoQ highlights the importance of germline sequencing for accurate cancer diagnosis and treatment. This approach helps differentiate between tumor-derived mutations and clonal hematopoiesis (CH) mutations, leading to more precise treatment decisions. ➡️ Read the full story: https://lnkd.in/ezM6KXWx #cancer #cancercare #cancerdiagnostics #diagnostics #cancerresearch
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New research by Dr. Karina Eterovic, MSc, PhD, NYS CoQ highlights the importance of germline sequencing for accurate cancer diagnosis and treatment. This approach helps differentiate between tumor-derived mutations and clonal hematopoiesis (CH) mutations, leading to more precise treatment decisions. ➡️ Read the full story: https://lnkd.in/eaE8AR4P #cancer #cancercare #cancerdiagnostics #diagnostics #cancerresearch
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📈 In 2022, there were 2.3 million women diagnosed with #breastcancer, a #cancer with diverse molecular signatures. We know that some genomic alterations in breast cancer are clinically actionable with targeted therapies. ✅ Understanding and testing for these biomarkers is the key to improving diagnosis and treatment. Learn more about how we can support your breast cancer testing 👉 https://lnkd.in/eS_3sMfM
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Cancer Precursor Project – Characteristics Of Premalignant Precursors, Part 5b (Hematopathology) Hematologic malignancies only rarely have precursors. We have identified only 6 precursors associated with 207 distinct hematologic malignancies (i.e., leukemias and lymphomas arising in the bone marrow and lymphoid tissue) and these precursors typically are either not morphologic (meaning the cancer cells do not appear different microscopically between the precursor and the malignancy) or are rare. The link to the full essay with images can be found on our blog at https://lnkd.in/e_fzSWCU #Cancer #CancerResearch #CuringCancerNetwork #Pathology
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A recent study presented at the 2024 American Association for Cancer Research (AACR) Annual Meeting reported the development of an exosome-based liquid biopsy that, when combined with the biomarker CA 19-9, could detect 97% of stage I to II pancreatic cancers. This method leverages exosomes, which are vesicles shed by cells, containing microRNAs and cell-free DNA, to create a robust signature for early detection. . #liquidbiopsy #pancreaticcancer #cancer #dna #exosome . 📚 https://lnkd.in/eYGFic-8
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Epigenetics Update – "Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth" https://bit.ly/4er5iic These data demonstrate an examples of a super-silencer and revealed that a combinatorial inhibitor can disrupt super-silencers, potentially leading to cancer ablation. #Epigenetics #Cancer #ChromatinStructure --- Explore heterogeneity in aging and disease; see how at: http://epigenome.us
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Malignant phyllodes tumors are rare breast tumors with few treatment options. Using Caris testing, a study led by Rani Bansal, MD and Dr. Laura Rosenberger from the Duke Cancer Institute shows how comprehensive molecular testing of phyllodes tumors can reveal targeted treatment opportunities. Learn more: https://lnkd.in/dxwAfacx
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Cancer is a complex disease with a wide distribution of mutations. To capture this data, single-cell analysis has become a ubiquitous tool for characterising tumours. This blog showcases how Hanlee and team developed a method to link mutations to phenotypes, aiding in identifying driver genes behind cancer. Read how long #nanopore reads provided more comprehensive data to uncover novel information about the mechanisms of #cancer. What you're missing matters. #WYMM #SwitchON Find out more: https://bit.ly/3DjyWrH
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Lung Cancer Panel contains essential genes that are in tyrosine kinase receptor pathways like ALK, KRAS, MET, MEK and EGFR. This panel sequences up to 29 genes, uses next-generation sequencing (NGS) and can be done on FFPE tissues. For detailed information, you can contact us: 🌐 www.theracision.com 📧 [email protected] #theracision #cancer #lungcancer #cancerdiagnosis
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The Importance of Early Molecular Analysis and Detection. Cervical cancer can be life-threatening, but with advancements in medical technology, early detection through molecular analysis offers hope for a positive outcome. Modern molecular techniques can identify the presence of cancer biomarkers at the earliest stages, allowing for prompt intervention before the disease progresses. By catching cervical cancer early, the chances of successful treatment and long-term survival improve dramatically. Don’t wait – take action today. Early detection might just save your life! https://f420.ai/ #cervicalcancer #CANCER #cervical
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I am happy to share our latest work, which analyzes and discusses the antitumoral role of natural compounds on the tumor suppressor protein p53. The p53-MDM2 pathway plays a pivotal role in tumor suppression and cancer progression. This review explores their interaction, roles in cellular processes, and disruption in cancer. It highlights natural products as potential therapeutic agents, categorizing them based on their mechanisms of modulating p53-MDM2 activity and emphasizing their potential in targeting this pathway for cancer therapy. Enjoy your reading #p53 #tumorsuppressor #naturalcompounds #cancer #reviewarticle
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