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CSF Questions

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2 views3 pages

CSF Questions

Uploaded by

subashzerstorer5
Copyright
© © All Rights Reserved
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Download as DOCX, PDF, TXT or read online on Scribd
Download as docx, pdf, or txt
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DEPARTMENT OF PATHOLOGY

Cerebrospinal Fluid OSPE Charts


(Competency: 35.3)
CHART A

A 32 year old female came to OPD with high fever for the past 12 hours with history of severe headache,
confusion, photophobia and neck stiffness. She has no significant past medical history and is not on any
medication.

CSF findings:

Normal

Naked eye appearance Cloudy

Opening pressure 300 mm H₂O in lateral decubitous position. 90-180 mm of water

Leucocyte count 3000 WBCs/ ml (>95% Neutrophils) 0-5 Wbcs/ml

Glucose level < 40% of serum glucose 60% of serum glucose

Protein level 3 g/L 15–45 mg/Dl

Questions: (1 mark each)

1. What is the most likely diagnosis? Give justifications.

2. Name any two organisms causing the above condition in elderly?

3. What is the cause of decrease in the CSF glucose level?

4. What is Xanthochromia?

5. How do you differentiate between cerebral hemorrhage and traumatic tap when the CSF is bloody?
DEPARTMENT OF PATHOLOGY
Cerebrospinal Fluid OSPE Charts
(Competency: 35.3)
CHART B

A 38-year-old female presents with 24 hours of headache, photophobia and mild neck stiffness, in
addition to stuffy running nose and congestion.She had perianal tenderness and rashes which on
examination revealed herpetic lesions.

CSF findings:

Normal

Naked eye appearance Clear

Opening pressure 300 mm H₂O in lateral decubitous position. 90-180 mm of water

Leucocyte count 150 cells /µL (Predominantly lymphocytes) 0-5 Wbcs/ml

Glucose level Normal 60% of serum glucose

Protein level 12 g/L 15–45 mg/Dl

Questions: (1 mark each)

1. What is the most likely diagnosis. Give justifications?


2. Enumerate the histological findings of the above condition?
3. Name two organisms causing Viral meningitis?
4. What are the routes of spread of microbes to enter the nervous system?
5. Define Aseptic meningitis?
DEPARTMENT OF PATHOLOGY
Cerebrospinal Fluid OSPE Charts
(Competency: 35.3)
CHART C

4 year old boy presented with fever, generalized body pain lasting for one month. On physical
examination multiple cervical and inguinal lymphadenopathy were found.

CSF findings:

Normal

Naked eye appearance Cob web appearance

Opening pressure 300 mm H₂O in lateral decubitous position. 90-180 mm of water

Leucocyte count 3000 WBCs/ ml (Predominantly 0-5 Wbcs/ml


lymphocytes)
Glucose level < 40% of serum glucose 60% of serum glucose

Protein level 3 g/L 15–45 mg/Dl

Questions:

1. What is the most likely diagnosis. Give justifications? (1 mark)

2. List down the broad classification of meningitis. (1 mark)

3. What is the definite investigation for identifying the causative organism? (1 mark)

4. What any 4 indications of lumbar puncture ? (2 marks)

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