ANALYTICAL CHEMISTRY PRE-BOARD EXAM

1. How many significant figures does this number have: 104,000 ?

A. 3 B. 4 C. 5 D. 6

2. Convert this number to PROPER scientific notation: 0.000780 x 10-8

A. 7.80 x 10-12 B. 7.80 x 10-11 C. 7.80 x 10-4 D. 7.80 x 10-5

3. Using proper scientific notation, how would you round the number 9.9813 x 10-5 to two
significant figures?
A. 10. B. 9.9 x 10-5 C. 1.0 x 10-5 D. 1.0 x 10-6

4. Using the rule for multiplication & division, what is the answer to this calculation:
(8.090 mg) ÷ (0.009 mL) = ?
A. 898.9 mg/mL B. 899 mg/mL C. 9.0 x 102 mg/mL D. 900 mg/mL

5. The answer to the calculation below should be reported to how many significant figures?
[(97+19.5)/( 434.97)] =
A. 2 B. 3 C. 4 D. 5

6. The law that regulates the practice of chemist and chemical technician in the Philippines
A. RA 10765 B. RA 10567 C. RA10657 D. RA 10675

7. Convert 110.00oC to oF:

A. 43.3oF B. 43.3oF C. 43.33oF D. 43.333oF

8. A chemist measured the mass of a wire using an analytical balance with the least count 0.001
g. The measured value should be recorded as:
A. 5.3200 cm B. 5.3 cm C. 5.32 cm D. 5.320 cm

9. What do we mean by ethics?

A. Moral judgments B. Determinants of what is right or wrong
C. Rules or standards governing a profession D. All

10. The study of ___, as contrasted with legal, obligations is called ethics.
A. Behavior B. Moral C. Business D. all of the above

11. __________ are beliefs and attitudes we have that can actually conflict with our ethical
decision.
A. Morals B. Principles C. Virtues D. Values

12. The unit for the measurement of density?

A. g/mL B. g/mol C. g/mg D. All

13. 454 mg is equivalent to ________ kg?

A. 4.5x10-4 B. 4.54x10-4 C. 4.540x10-4 D. 4.00x10-4

14. The type of biological Safety Levels which requires a separate building.
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

A. BSL 1 B. BSL2 C. BSL 3 D. BSL 4

15. Which of the following is not a chemical-related health hazard?

A. Carcinogenicity B. Reactivity C. Corrosivity D. Toxicity

16. This hazard symbol is used when something is:

A. Corrosive B. Almost empty C. Flammable D. Highly acidic

17. If you transfer chemicals from a labeled container to a portable container, you don’t need to
comply with standard hazardous material labeling requirements when:
A. You hand the container off to someone else
B. You leave the work area before using the materials
C. You don’t use the materials before the end of your work shift
D. None of the above

18. Sections of the SDS regulated by OSHA

A. 16 B. 12 C. 11 D. 4

19. Section of the SDS that describes Hazard Identification

A. Section 1 B. Section 2 C. Section 3 D. Section 4

20. SDS Section which gives recommendations for the proper PPE
A. Section 4 B. Section 6 C. Section 8 D. Section 10

21. Which of the following statements is true of the pictograms on HCS labels?
A. Pictograms on HCS labels are identical to those used on DOT transport labels and may have
various background colors.
B. Consist of four bars that are color-coded as blue, red, yellow, and white to match hazard.
C. HCS pictograms are required and standardized red square-on-points with black hazard
symbols and white backgrounds.
D. All of the Above

22. A document that lists information relating to occupational safety and health for the use of
various substances and products.
A. HMIS B. SDS C. HCP D. All

23. The type of toxicity cause by long-term exposure:

A. Acute B. Chronic C. Local D. Systemic

24. An organic compound the production of which was banned in the US in 1979 due to it’s
environmental toxicity and classified as persistent organic pollutant
A. PAH B. Dioxin C. PCB D. Benzene

25. The most electronegative atom:

A. Fluorine B. Chlorine C. Oxygen D. All
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

26. Referring to the periodic table, select the most electronegative atom in the given set: K, Mg,
Ca and Na:
A. Na B. Ca C. Mg D. K

27. Referring to the periodic table, arrange the following elements in terms of increasing
electronegativity:
Ca, Cs, S, Sc & Si
A. Ca, Cs, S, Sc, Si B. Cs, Ca, Sc, Si & S C. S, Si, Sc, Ca and Cs. D. Si, S, Sc, Cs Ca

28. Referring to the periodic table, which, of the set of elements has the highest ionization
energy:
S, Al, Br, Se
A. Se B. Br C. S D. Al

29. Referring to the periodic table, which of the set of elements has higher electron affinity:
Br, Se, S, Al
A. Se B. Br C. S D. Al

30. Arrange the given according to increasing ion size: Cation (C), Anion (A), Neutral Atom (N)
A. C, A, N B. C, N, A C. N, C, A D. A, N, C

31. 39 +
19𝐾 , potassium as given has a number of electrons equal to:
A. 20 B. 21 C. 18 D. 19

32. The formula for hydrosulfuric acid is:

A. H2S B. H2s(aq) C. H2SO3(aq) D. H2SO4(aq)

33. 27 +3
13𝐴𝑙 , Aluminum ion has number of electrons equal to:
A. 13 B. 27 C. 10 D. 16

34. The sub atomic particle with negative charge:

A. Proton B. Neutron C. Positron D. Electron

35. The region where protons can be found:

A. Shell B. Neutron C. Nucleus D. Energy Level

36. In the reaction, H2 + O2 → H2O, the limiting reactant is:

A. H2 B. O2 C. H2O D. None
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

37. The limiting reactant is the:

A. One with lower mole ratio B. One with lower number of moles
C. One with lower molar mass D. All

38. the correct formula for Aluminum Bicarbonate is:

A. Al2HCO3 B. Al2(HCO3)3 C. Al(HCO3)3 D. Al2(CO3)3

39. The formula for Iodic Acid is:

A. HIO3(aq) B. HIO3 C. HIO4(aq) D. HIO4

40. The correct name for the chemical formula, PCl6 is:
A. Monophosphorus Hexachloride B. Phosphorus Chloride
C. Phosphorus Hexachloride D. None

41. Which of the following compounds has ionic bond:

A. CO2 B. HCl C. Br2 D. CaF2

42. Which of the following compounds has covalent bond:

A. CdI2 B. I2 C. NaCl D. None

43. What is the maximum number of grams of NH4SCN(s) that can be prepared from 9.00 g of
CS2(l) and 3.00 g of NH3(g)? The equation for the reaction is: C=12; S=32; H=1; N=14
CS2(l) + 2NH3(g) ⟶ NH4SCN(s) + H2S(g)
A. 6.7g B. 6.71g C. 6.710g D. 6.700g

44. In the given chemical reaction, identify which type of reaction:

Zn(s) +AgNO3(aq) ⟶Ag(s) + Zn(NO3)2(aq)

A. Synthesis B. Decomposition C. Single Replacement D. Double

Replacement

45. In the given reaction: CaCO3+ HCl(aq) → CaCl2(aq) + CO2 + H2O the coefficients for the
balanced reaction:
A. 2, 1, 2, 2, 2 B. 2, 4, 2, 2, 2 C. 1, 2, 1, 1, 1 D, 2, 2, 2, 2, 2

46. The correct chemical formula for calcium sulfate decahydrate is:
A. CaSO4∙2H20 B. CaSO4∙20H20 C. CaSO4∙8H20 D. CaSO4∙10H20

47. The members of the group 2 elements:

A. Alkali Metals B. Alkaline Earth C. Chalcogen D. Halogen

48. Can conduct electricity only at higher temperatures. They are:

A. Metals B. Non-Metals C. Metalloids D. Conductors

49. 3.54 g H2SO4 has equivalent number of moles: H=1, S=32, O=16
A.0.0361 mol B. 0.036 mol C. 0.040 mol D. 0.04 mol
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

A solution is prepared by dissolving 464 g of NaOH (MM=40) in water and then diluting to one
liter. The density of the resulting solution is 1.37 g/ml. Answer questions 50 to 54:

50. The % mass of NaOH is:

A. 33.87% B. 11.6% C. 50.33% D. 12.80%
51. The molarity of the solution is:
A. 33.87 M B. 12.80 M C. 11.6 M D. 50.33 M
52. The molality of the solution is:
A. 33.87 m B. 12.80 m C. 11.6 m D. 50.33 m
53. The mole fraction of NaOH is:
A. 11.6 B. 0.187 C. 0.813 D. 12.80
54. The mole fraction of H2O is
A.0.187 B. 0.813 C. 33.87 D. 11.6

55. 234 g of sodium chloride is reacted with sulfuric acid to produce hydrogen chloride gas and
sodium sulfate.
Molar masses (g/mol): NaCl 58.45 H2SO4 98.00
HCl 36.45 Na2SO4 141.86

Which of the following statement is not true:

A. The balanced chemical equation is 2NaCl + H2SO4 -----> 2 HCl + Na2SO4
B. According to the balanced equation, 2 moles of NaCl produce 2 moles of HCl
true
C. From 234 g of NaCl, 146 g of HCl is formed.
D. 2 moles of sodium sulfate are formed for every mole of NaCl reacted.

56. Which of the following statements about acids and bases is not true:
A. Water undergoes autoionization.
B. Strong acids and strong bases are ionized completely in dilute aqueous solutions.
C. The strength of an acid or a base is measured by the extent of its ionization in solution.
D. Strong acids form strong conjugate bases.

57. Which statement about Arrhenius acids is FALSE?

A. Their water solutions are called aqueous acids.
B. They are molecular compounds with ionizable hydrogen atoms.
C. Their pure aqueous solutions are electrolytes.
D. They increase the concentration of hydroxide ions in aqueous solution.

58. Strong bases are:

A. strong electrolytes. B. nonelectrolytes C. weak electrolytes D. also strong acids

59.What is the pH of a 1 x 10–4 M HCl solution?

A. 4 B. 8 C. 6 D. 10

60.What is the pH of a 1 x 10–5 M KOH solution?

A. 3 B. 9 C. 5 D. 11
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

61. What is the molarity of an HCl solution if 50.0 mL is neutralized in a titration by 40.0 mL
of 0.400 M NaOH?
A. 0.200 M B. 0.320 M C. 0.280 M D.. 0.500

62. Which are the correct products for these reactants HCl + NaOH
A. HOH + ClNa B. H3O + NaCl2 C. NaCl + H2O D. NaOH + Cl

63. The symbol for Silver element is:

A. S B. Si C. Sr D. Ag

64. Which of the following substance is a salt:

A. HCl B. NaOH C. NaBr D. None

65. Which of the following compounds contains an ionic bond?

A.NH3 B. H2O C. CaO D. H2

66. Systematic errors may arise from avoidable sources, except

A. contamination, reagent impurities,
B. wrongly calibrated instruments, instrumental mal- functions,
C. poor sampling techniques, errors in calculations
D. electronic noise in the circuit of an electrical instrument

67. Systematic errors primarily influence a measurement's _________.

A. Accuracy B. Precision C. Standard deviation D. Mean

68. An improperly calibrated thermometer may give accurate readings within a certain
temperature range, but become inaccurate at higher or lower temperature.
A. Random error B. Gross error C. Systematic error D. Analyst error

69. An error caused by not setting an instrument to zero prior to its use is called an ______ error.
A. Offset error B. Random error C. Gross error D. Systematic error

70. In the decomposition and dissolution of solids during sample preparation, which of the
following is expensive and often the last resort?
A. Acid treatment using oxidation B. Fusion technique
C. Dissolution using ultrasound and appropriate solvent D. Simple dissolution

71. Reliability of the results decreases with a decrease in the level or concentration of the:
A. matrix B. analyte C. reactant D. product

72. Properties of nitric acid making it the preferred acid for digesting samples for the analysis of
metals
A. acts as a strong acid B. as an oxidizing agent
C. does not form insoluble compounds with metals/nonmetals D. All of the above

73. Primary sample preparation method for organics

 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

A. Sonication B. Acid-digestion C. Extraction D. All of the above

74. Possible sources of contamination during sample preparation include:

A. Reagents (tracers) B. Glassware/equipment
C. Cross-contamination between high- and low-activity samples D. All of the above

75. Containers that should not be used for dry ashing because the elevated temperatures
exceed the melting point of these materials
A. zirconium B. platinum C. Glass and plastic D. porcelain

76. Determinate errors, also called ____________.

A. Bias B. Random error C. Gross error D. Systematic error

77. An error that is known to have occurred but was unavoidable

A. Bias B. Random error C. Gross error D. Systematic error

78. The maximum holding time for acid preserved samples that will be subjected to
determination of metals is
A.3 months B. 1 week C. 6 months D. 48 hours

79. Refers to the repeatability of a measurement.

A. Accuracy B. Precision C. Specificity D. Mean

80. A change in the analytical signal caused by anything in the sample other than analyte.
A. matrix effect B. interference C. absorbance D. transmittance

81. Medium containing analyte.

A. reactant B. matrix C. solute D. reference material

82. The total error of an analytical result is the sum of

A. sampling B. sample preparation C. analytical errors D. All of the above

83. The holding time for samples for metal determination preserved using nitric acid, 4 mL of
dilute 3:1 is
A. 28 days B. 2 weeks C. 3 days D. 1 year

84. The following numerical results were obtained in a given laboratory experiment: 0.09376,
0.09358, 0.09385, and 0.09369. Calculate the relative parts per thousand standard deviation
A. 1.2 B. 1.1 C. 1.3 D. 1.4

85. The following are analytical strategy steps except for one.
A. obtain the sample B. prepare the sample
C. carry out the analysis method D. releasing of results

86. A student determines the weight of an object on an analytical balance to be 12.2843 g. The
actual weight, unknown to the student or to anyone else, is 12.2845 g. What kind of error is this?
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

A. Determinate B. indeterminate D. gross D. none of the above

87. A given analytical test was performed five times. The results of the analysis are represented
by the following values: 6.738, 6.738, 6.737, 6.739, and 6.738%.. The result are
A. Accurate B. precise
C. not precise D. not precise and not accurate

88. Process by which a sample population is reduced in size to an amount of homogeneous

material that can be conveniently handled in the lab in which the composition is representative of
the population.
A. Selection B. monitoring C. sampling D. segregation

89. A sample that has all the characteristics in exactly the same proportion as the bulk sample
where it came from:
A. representative sample B. test sample C. gross sample D. subsample

90. Locating the adulterated portion of the lot for sampling is an example of
A. random sampling B. selective sampling
C. composite sampling D. stratified sampling

91. In gravimetric analysis,

A. the mass of a solution is used to calculate the quantity of the original analyte.
B. the mass of a product is used to calculate the quantity of the original analyte.
C. the mass of a product is used to calculate the quantity of the impurity.
D. none of the above

92. Glass container is not suitable for

A. inorganic trace analyses B. oil and grease determination
C. microbiological analyses D. all of the above

93. To increase/decrease analyte concentration, pre-concentration is needed for almost all trace
analysis, ________ is used for the analysis of highly contaminated samples so the
concentration falls within the calibration range.
A. centrifugation B. separation C. dilution D. all of the above

94. Chemical derivatization is used to increase or decrease volatility for _________ analysis
A. AAS B. GC and HPLC C. PCR D. X-ray Diffraction

95. Acid digestion via hot-plate digestion or microwave-assisted is one way of sample
preparation in the analysis of
A. Total metal B. Bioactive compounds C. Alcohols D. Sugars

96. GFAA (Graphite Furnace Atomic Absorption) do not use HCl since Cl- interferes. Diluted
______ acid is used.
A. Phosphoric Acid B. Acetic acid C. Nitric Acid D. Sulfuric Acid
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

97. Partitioning of analytes between water phase and organic phase

A. Liquid-liquid extraction B. Soli phase extraction
C. Ultrasonic extraction D. Pressured Fluid Extraction (PFE)

98. The original undivided sample that was taken directly from the bulk system being
characterized.
A. bulk sample B. test sample C. subsample D. laboratory sample

99. A primary sample is the same as

A. Subsample B. test sample C. bulk sample D. laboratory sample

100. If a water sample is to be analyzed for trace levels of metals, glass container for sampling
and storage is inappropriate due to the following reasons except for one.
A. it could leach trace level metals and contaminate the sample
B. it can absorb some analytes
C. very impure as compared to quartz, PTFE, PP
D. losses of elements due to adsorption are very high

101. Sample preparation depends on

A. the nature of the sample
B. the analyte to be determined and their concentrations/amounts
C. the desired determination precision and accuracy.
D. all of the above

102. An acid that turns paper towel black, a very dense syrupy liquid that gets especially hot
when mixed with water is
A. Sulfuric Acid B. Nitric Acid C. Hydrochloric Acid D. Perchloric Acid

103. PEL stands for

A. personal exposure limit
B. permissible exposure limit
C. permissible exposure time length
D. none of the above

104. What does SPE stand for?

A. Sample preparation evaluation B. Solid phase extraction
C. Solid phase evaporation D. Sample processing experiment

105. The label CORROSIVE on a chemical container indicates

A. that the material is an oxidant
B. that contact destroys living tissue as well as equipment
C. that the material can degrade rapidly upon exposure to air
D. All of the above

06. When diluting an acid with water,

 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

A. do it quickly, so that a cool fountain of toxic material is ejected from the flask
B. do not stir the flask, because it might break
C. always add acid to water, not water to acid, so that the heat of reaction can be
controlled
D. None of the above

107. When operating a fire extinguisher, remember the mnemonic PASS. PASS represents the
steps used to properly operate the extinguisher and it stands for which of the following?

A. Pin, Aim, See, Swing

B Pull, Access, Seize, Sweep
C. Plan, Access, Squeeze, Swing
D. Pull, Aim, Squeeze, Sweep

108. A "Class-A" fire extinguisher can be used to treat fires involving _____ as fuel sources.

A. ordinary combustibles (woods, plastics, etc.)

B. flammable or combustible liquids
C. electrical equipment
D. combustible metals

109. Given the unbalanced equation below, how many grams of carbon dioxide will be produced
from one mole of glucose and six moles of oxygen? C6H12O6+O2→CO2+H2O
A. 12 B. 4 C. 6 D.10

110. A blank used to test the integrity of reagents used in the laboratory. For example, a new
batch of solvent might be tested for impurities, or distilled or deionized water would be tested to
ensure that it is pure.
A. reagent blank B. field blank C. surrogate D. instrument blank

111. Which sampling term is incorrectly defined?

A. laboratory sample – smaller, homogeneous sample taken from the bulk and has the same
composition as the bulk
B. lot – the total material from which samples are taken
C. aliquot – small portions of the bulk sample taken for individual analysis
D. sample preparation – the series of steps that convert a representative bulk sample into a form
suitable for analysis

112. The liquid solution containing the analyte is passed through a cartridge containing a solid
sorbent.
A. Liquid-liquid extraction B. solid phase extraction C. purge-and-trap D. none of the above

13. An example of a nonpolar organic solvent that is often used for extracting analytes from
aqueous solutions
A. hexane B. acetic acid C. n-butanol D. water
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

114. The analyte in a sample may be too concentrated or too dilute for the chosen method. If it is
too concentrated, a dilution with a compatible solvent may be performed. The dilution should be
performed with _______________glassware and with good analytical technique so that the
dilution factor is known and accuracy is not diminished.
A. graduated glassware B. graduated plastic wares C. volumetric glassware D. nesslers tubes

115. A ___________is a substance used in a chemical reaction in an analytical laboratory

because of its specific applicability to a given system or procedure
A. reagent B. sample C. media D. test kits

116. Choose the sample that would be best dissolved by HNO3.

A. NaCl B. Iron ore C. Copper metal D. Aluminum Oxide

117. From the following list, choose those samples that would be best dissolved by HCl.
A. NaCl B. Iron ore C. Gold metal D. Aluminum Oxide

118. Calculate the equivalent weight and normality for a solution of 6.0 M H3PO4 given the
following reactions:
A). H3PO4(aq) + 3OH–(aq) PO43–(aq) + 3H2O(l)
B). H3PO4(aq) + 2NH3(aq) HPO42–(aq) + 2NH4+(aq)
–
C). H3PO4(aq) + F (aq) H2PO4–(aq) + HF(aq)
A. (a) 18 N, (b) 12 N and (c) 6N B. (a) 12 N, (b) 18 N and (c) 6N
C. (a) 6 N, (b) 12 N and (c) 18N D. (a) 16 N, (b) 12 N and (c) 3N

119. What is the molality of solution made by dissolve 25 g of NaCl in to 2.0 Liter of water.
Assume the density of water d = 1.0 g/mL (= kg/L).
A. 0.210 m B. 0.250 m C. 0.211 m D. 0.214 m

120. The amounts of all constituents in the samples were determined

A. Complete (or ultimate) analysis B. Partial analysis
C. Elemental analysis D. All of the above

121. Implies that the constituent determined was present in high concentration
A. Trace analysis B. Macro analysis C. Elemental analysis D. All of the above

122. Quantitative chemical analysis of weighing a sample, usually of a separated and dried
precipitate.
A. Titrimetric analysis B. Volumetric analysis C. Gravimetric analysis D. Elemental analysis

123. A chemical grade of highest purity and meets or exceeds purity standards set by American
Chemical Society
A. Technical grade B. Laboratory grade C. Pure or practical grade D. ACS grade

124. Which of the following is a primary standard for use in standardizing bases?
A. Ammonium hydroxide B. Sulfuric acid
C. Acetic acid D. Potassium hydrogen phthalate
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

125. How would you prepare 500.0 mL of 0.2500 M NaOH solution starting from a
concentration of 1.000 M?
A. Transfer 125 mL from initial solution (1.000 M) and complete with solvent to 500.0 mL.
B. Transfer 121 mL from initial solution (1.000 M) and complete with solvent to 500.0 mL.
C. Transfer 122 mL from initial solution (1.000 M) and complete with solvent to 500.0 mL.
D. Transfer 112 mL from initial solution (1.000 M) and complete with solvent to 500.0 mL.

126. A student performs five titrations and obtains a mean result of 0.110 M, with a standard
deviation of 0.001 M. If the actual concentration of the titrated solution is 0.100 M, which of the
following is true about the titration results?
A. Accurate but not precise B. Precise but not accurate
C. Both accurate and precise D. Neither accurate nor precise

127. How many grams of Sodium Persulfate (Na2S2O8) required to prepare a 1 L solution of
Sodium Persulfate with concentration of 10% (w/v). This solution is widely used as oxidizing
reagent for Total Organic Carbon analyzer (TOC).
A. 100 g of Sodium Persulfate B. 101 g of Sodium Persulfate
C. 102 g of Sodium Persulfate D. 99 g of Sodium Persulfate

128. A solution has been prepared by transfer 60 mL from Ortho-phosphoric acid 85 % (v/v)
H3PO4 and dilute to 1.0 L, what is the concentration of the new solution.
A. 10.10% B. 9.25% C. 12.2% D. 5.10%

129. A student has got three stock standard solutions of 3 different elements, zinc (Zn) 2000
ppm,
cadmium (Cd) 1500 ppm and lead (Pb) 1000 ppm. A student took 10 mL from each solution
and transfers it to 200 mL volumetric flask then completed to total volume with solvent. What
is the final concentration of each element in the diluted mix solution?
A. 50 ppm Zinc, 32 ppm Cd, 25 ppm Pb B. 100 ppm Zinc, 75 ppm Cd, 50 ppm Pb
C. 75 ppm Zinc, 75 ppm Cd, 50 ppm Pb D. 100 ppm Zinc, 25 ppm Cd, 25 ppm Pb

130. Bidirectional harpoons or double arrows (⇆) should be used to indicate ________ reactions
A. one sided B. resonance C. dynamic D. reversible

131. In the preparation of 1 liter of 1.0 N acid from 35% Hydrochloric Acid, what weight of the
impure acid should be taken, assuming standardization in the recommended manner?
A. 101.29 B. 113.29 C. 111.29 D. 124.89

132. A few ways in which solution composition can be described are as follows.
A. Molarity B. Normality C. Molality D. All of the above

133. The substance which does the dissolving and must be greater than 50% of the solution.
A. Solvent B. solute C. mixture D. solution

134. Naphthalene (C10H8) is one of aromatic hydrocarbons measured by GC-MS. If molecular

weight of naphthalene is 128.6 g/mol; how many milligrams are required to prepare 100 mL of
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

2,000 ppb stock standard solution of naphthalene from powder Naphthalene (purity of 91.5 %
w/w)?
A. 2.18 B. 2.1858 C. 2.186 D. 2.1859

135. A student has to measure out 9.40 mL of a liquid and selects a 100 mL graduated cylinder.
To improve the accuracy of the measurement, it would be most effective to:
A. take the average of multiple measurements using the graduated cylinder.
B. measure the liquid using a 25 mL graduated cylinder instead.
C. estimate the measurement obtained from the graduated cylinder to an additional
significant figure.
D. measure the liquid using a 10 mL graduated pipette instead.

136. Nitrate (NO3-) anion solution prepared by dissolving 3.0 g of KNO3 in 250 mL of water.
What is the concentration of Nitrate ion, express the concentration in Molarity and ppm.
A. 0.1187 M, 7359.05 ppm B. 0.1190 M, 7349.05 ppm
C. 0.1107 M, 7459.00 ppm D. 0.1120 M, 7400.00 ppm

137. The number of formula mass of any solute dissolved in 1 liter of solution
A. Formality B. normality C. molality D. molarity

138. A 0.217 g sample of HgO (molar mass = 217 g) reacts with excess iodide ions according
to the reaction. Titration of the resulting solution requires how many mL of 0.10 M HCl to reach
equivalence point? HgO + 4 I− + H2O →HgI4 2- + 2 OH−
A. 1.0 mL B. 10 mL C. 20 mL D. 50 mL

139. If the theoretical yield for a reaction was 156 grams and I actually made 122 grams of the
product, what is my percent yield?
A. 78.2% B. 128% C. 19.0% D. none of these

140. The method of standardization can be used if a _______________ reacts quantitatively with
the reagent needed in the standard solution.
A. primary standard B. secondary standard C. working standards D. intermediate solution

141. You have a stock solution of 15.8 M HNO3. How many mL of this solution should you
dilute using only a graduated pipette to make 100.0 mL of .250 M HNO3?
A. 1.58 B. 1.582 C. 1.50 D. 1.583

142. If 56.0 g of Li reacts with 56.0 g of N2, 93.63 grams of Li3N can be produced. How many
grams of Nitrogen remains? What is the limiting reactant?
A. 19.3 g; Nitrogenb. B. 18.3 g N; Lithium C. 20.3 g N; none D. 18.39 ; Lithium

143. HCl cannot be considered to be a primary standard because of its gaseous form at room
temperature, but its solutions may be standardized against anhydrous ______.
A. NaSO4 B. NaHCO3 C. Na2CO3 D. All of the above
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

144. When making a solution from a solid reagent, if necessary, dry the solid reagent on a clean,
oven dried, watch glass at 105 ºC for 2 hours and cool it in a desiccator.
A. 121 ºC B. 105 ºC C. 80 ºC D. 118 ºC

145. Requirements of a primary standards.

A. High Purity, 99.9% or better B. Stability in air
C. Absence of hydrate water D. All of the above

146. Blank samples are prepared so that you have a measure of the amount that needs always to
be added to or subtracted from the end point to achieve the ________point.
A. titration error B. equivalence C. accuracy D. precision

147. A specially manufactured analytical reagent of exceptional purity for standardizing

solutions and preparing reference standards.
A. working standard B. secondary standard
C. primary standard D. internal quality control standard

148. A reagent that meets the standards of purity established by the manufacturer. The certificate
of analysis is on the label.
A. certified reagent B. secondary standard
C. primary standard D. internal quality control standard

149. Chemicals of reasonable purity for applications that have no official standard for purity.
A. Analyzed Reagent B. ACS grade C. Technical Grade D. Practical grade

150. Solvents of suitable purity for use in spectrophotometric procedures. A certificate of

analysis is on the label.
A. Spectro grade B. HPLC grade C. Technical Grade D. Practical grade

151. Chemicals of sufficiently high quality to be suitable for use in some syntheses. Organic
chemicals of this grade may contain small amounts of intermediates, isomers, or homologs.
A. USP or NF grade B. HPLC grade C. Technical Grade D. Practical grade

152. When an open bottle of _________________ sits next to an open bottle of ammonium
hydroxide, thick white fumes form.
A. Nitric acid B. Hydrochloric acid C. Sulfuric acid D. Hydroflouric acid

153. What acid is a highly corrosive mineral acid and is also known as aqua fortis (Latin for
"strong water") and spirit of niter, is
A. Nitric acid B. Hydrochloric acid C. Sulfuric acid D. Hydroflouric acid

154. ____________________ diffuses through skin and is especially bad when it gets under the
fingernails.
A. Nitric acid B. Hydrochloric acid C. Sulfuric acid D. Hydroflouric acid

155. _____________________ is used to dissolve the sample for the Kjeldahl analysis.
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

A. Nitric acid B. Hydrochloric acid C. Sulfuric acid D. Hydroflouric acid

156. A mixture of concentrated HNO3 and HCl in the ratio of 1:3 HNO3:HCl is
A. muriatic acid B. oil of vitriol C. aqua regia D. none of the above

157. If a given procedure calls for a pure methyl alcohol of the highest grade, then the
___________ should be used.
A. ACS grade or AR grade B. Laboratory grade
C. Technical grade D. USP grade

158. What classical method of analysis is characterized by the fact that the measurement of
weight is the primary measurement, usually the only measurement made on the sample, its
components, or its reaction products.
A. Volumetric method B. Titrimetric method
C. Gravimetric method D. Instrumental method

159. What is the percent loss on drying if a sample weighs 4.5027 g before drying and 3.0381 g
after drying?
A. 32.527% B. 32% C. 32.53% D. 32.5%

160. The onset of a phase transition in a small region which can be the formation of a bubble or
of a crystal from a liquid.
A. Precipitation B. nucleation C. reprecipitation D. crystallization

161. Refers to a solution that contains more of the dissolved material than could be dissolved by
the solvent under normal circumstances.
A. Supersaturation B. nucleation C. reprecipitation D. none of the above

162. What type of balance uses an electromagnet to balance the object to be weighed on a single
pan?
A. macro balance B. electronic balance
C. mechanical balance D. none of the above

163. A balance that is used to obtain four or five digits to the right of the decimal point in the
analytical laboratory is called the (precision is ±0.1 or ±0.01 mg).
A. macro balance B. electronic balance
C. mechanical balance D. analytical balance

164. Refers to the process by which a balance is checked to see if the weight obtained for an
object is correct.
A. Validation B. verification C. calibration D. maintenance check

165. Gravimetric analysis methods proceed with the following steps:

A.The weight or volume of the prepared sample is obtained,
B. The analyte is either physically separated from the sample matrix or chemically altered
and its derivative separated from the sample matrix
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

C. The weight of the separated analyte or its derivative is obtained.

D. All of the above

166. This is an example of a loss through volatilization (evaporation) under temperature

conditions at which water would volatilize.
A. loss on drying B. loss on ignition C. loss on filtration D. none of the above

167. Ambient laboratory conditions are not the same to standard conditions, therefore the
volumes dispensed in volumetric glassware are often not the same as the manufacturer's
specifications, but within some acceptable limits determined by the manufacturer. This slight
variation in volume will cause a _________ error that are based on volume-volume or mass-
volume concentrations.
A. Random B. systematic C. gross D. all of the above

168. Glass cuvettes are typically for use in the wavelength range of visible light, whereas fused
quartz tends to be used for ____________ applications.
A. Microwave B. IR C. uv/visible D. none of the above

169. In this column type, the retention is governed by the interaction of the polar parts of the
stationary phase and solute.
A. reverse phase B. ion exchange C. column guard D. normal phase

170. A stable light source in AAS analysis, which is necessary to emit the sharp characteristic
spectrum of the element to be determined
A. Tungsten lamp B. hollow cathode lamp C. deuterium lamp D. Nerst blower

171. The HPLC column type in which molecules are separated according to size.
A. Ion exchange B. size exclusion C. normal phase D. reverse phase

172. Non Polar Reverse phase and C8 (octyl bonded silica) are commonly used for hydrophobic
Analytes in solid phase extraction. An example is
A. C18 (octadecyl bonded silica) B. Resins
C. Florisil D. alumina

173. Filters that can be heated and used in gravimetric analysis.

A. ordinary filter paper B. GFF
C. Sintered glass fibers D. none of the above

174. Objects cannot be weighed when hot or warm. But if you were to take a sample out and
wait for it to cool it would pick up moisture like that so put it in ________.
A. an oven B. a dessicator C. at room temperature D. fumehood

175. The following are common desiccants except for _______

A. Calcium Sulfate B. Ammonium Acetate
C. Calcium Chloride D. Magnesium Oxide
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

176. During ignition for ashing, muffle furnaces that go up to 1100oC are used primarily for this
and ________ is needed to contain the sample.
A. porcelain crucible B. evaporating dish C. beaker D. all of the above

177. In making standard solutions, ______ are used for measuring liquid with high accuracy.
A. Beakers B. volumetric flasks C. Erlenmeyer flasks D. Nesslers Tubes

178. Used for distillation or heating of liquids, allows uniform heating.

A. round bottom flask B. Erlenmeyer flask
C. test tube D. Florence flask

179. Most popular burettes are 10 mL, 25 mL and 50 mL types. Which has the highest
resolution?
A. 25 mL B. 10 mL C. 50 mL D. All of the above

180. Used for vacuum filtration using filter paper.

A. gooch crucible B. Buchner funnel C. rotary evaporator D. rubber aspirator

181. In chromatography, ________ is carried out on glass plates or strips of plastic or metal
coated on one side with a thin layer of adsorbent.
A. HPLC B. GC C. Paper Chromatography D. Thin Layer Chromatography

182. The nominal volume of water (or mercury) contained, or delivered by an article of
volumetric glassware, at its reference temperature.
A. Capacity B. liter C. mL D. uL

183. In verification of laboratory glassware, ________ is usually measured in terms of the

tolerance, which is the uncertainty in a measurement made with the glassware. Class A
volumetric glassware has a lower tolerance than Class B.
A. Mean B. accuracy C. difference D. precision

184. Glass apparatus that are generally received with calibration certificates from suppliers.
A. Class B B. Class A C. Erlenmeyer flasks D. Beakers

185. Refers to repeated drying steps until two consecutive weights agree to within a specified
precision, such as having two consecutive weights that do not differ by more than 0.25%.
A. loss on drying B. taring C. loss on ignition D. constant weight

186. Total solids involve measuring a volume of the water or wastewater into a preweighed
A. evaporating dish B. gooch crucible C. sintered crucible D. filter crucible

187. Equipment that work by the sedimentation principle, where the centripetal acceleration is
used to separate substances of greater and lesser density.
A. Rotary evaporators B. Centrifuges
C. Reciprocating shakers D. Rotary shakers
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

188. Also known as droppers or eye droppers, are used to transfer small quantities of liquids.
They are usually glass tubes tapered to a narrow point, and fitted with a rubber bulb at the top.
A. Pasteur pipettes B. graduated pipettes C. capillary tubes D. Bulb pippetes

189. Small, cylindrical plastic containers with conical bottoms, typically with an integral snap
cap. They are used in molecular biology and biochemistry to store and centrifuge small amounts
of liquid.
A. Eppendorf tubes B. capillary tubes C. microfuge tubes D. Falcon Tubes

190. A device used in chemical and biochemical laboratories for the efficient and gentle
evaporation of solvents. The system works because lowering the pressure lowers the boiling
point of liquids, including that of the solvent.
A. Rotary evaporators B. Centrifuges
C. Reciprocating shakers D. Rotary shakers

191. An essential item used in the distillation of liquid mixtures so as to separate the mixture into
its component parts, or fractions, based on the differences in their volatilities.
A. Condenser B. reflux apparatus
C. fractionating column or fractionation column D. rotary flask

192. Boiling chips are also known as

A. boiling stones B. boileezers C. anti-bumping granules D. all of the above

193. All proteins absorb electromagnetic radiation of wavelength around 190 nm, which
corresponds to a excitation in the protein molecule. In which region of the spectrum is this
wavelength found?
A. X-ray B. ultraviolet C. Visible D. Infrared

194. Chromatography is used to

A. Separate two or more compounds based on their polarities.
B. Separate two or more compounds based on their masses.
C. Separate two or more compounds based on how strongly they interact with other
compounds.
D. all of the above.

195. A food scientist has a sample of a plantoil and wants to determine if the oil contains
saturated or unsaturated fatty acids. Which of the following spectroscopic techniques would be
most useful for this purpose?
A.ultraviolet spectroscopy B.visible spectroscopy
C. infrared spectroscopy D. mass spectroscopy

196. The concentration at which the calibration curve departs from linearity by a specified
amount.
A. Limit of Blank B. Dynamic Range C. Limit of Linearity D. Limit of quantitation
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

197. A graphical representation of measuring signal as a function of quantity of analyte.

A. Calibration curve B. Quality Control Chart C. Absorbance Chart D. None of the above

198. What is the path of light through a spectrophotometer?

A. meter, photodetector, filter, sample, light source
B. meter, filter sample, photodetector, light source
C. light source, filter, sample, photodetector, meter
D. light source, sample, filter, photodetector, meter

199. With a “standard” sample with a known absorbance and concentration and a measured
absorbance, it is easy to determine an unknown concentration of †the same substance by.
A. Beer’s Law B. Lambert’s Law C. Faraday’s Law D. None of the above

200. The highest apparent analyte concentration expected to be found when replicates of a blank
sample containing no analyte are tested..
A. Limit of Detection B. Limit of Blank
C. Limit of Linearity D. Limit of Quantitation

201. Motion of the mobile phase through the stationary phase.

A. Elution B. Retention time C. Eluent D. Elution time

202. A phase which sample is dissolved in may be gas, liquid, or supercritical fluid
A. stationary phase B. reverse phase C. normal phase D. mobile phase

203. In spectrophotometric methods, the _________ isolates the specific spectrum line emitted
by the light source through spectral dispersion.
A. Monochromator B. prism C. sample compartment D. detector

204. In AAS method, If the sample concentration is too high to permit accurate analysis in
linearity response range, there are alternatives that may help bring the absorbance into the
optimum working range.
A. sample dilution
B. using an alternative wavelength having a lower absorptivity
C. reducing the path length by rotating the burner hand
D. All of the above

205. A technique for separating mixtures into their components in order to analyze, identify,
purify, and/or quantify the mixture or components.
A. Spectrocopy B. Chromatography C. Gravimetry D. Titrimetry

206. A “modified” stationary phase where polar solutes run fast i.e. reverse order.
A. Normal phase B. Reverse phase C. mobile phase D. none of the above

207. A graph showing the detectors response as a function of elution time : band’s shapes,
position, resolution
A. monitor display B. quality control chart C. calibration curve D. chromatogram
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

208. The pH meter glass probe has two electrodes, one is a glass sensor electrode and the
other is a _______electrode.
A. Reference B. anode C. cathode D. none of the above

209. Conductivity could be determined using the distance between the electrodes and their
surface
area using Ohm's law but, for accuracy, a calibration is employed using _____ of well-known
conductivity.
A. acid solution B. basic solution C. electrolytes D. buffer solution

210. The electrical conductivity of water is directly related to the concentration of dissolved
ionized solids in the water or
A. Total Suspended Solids B. Total Dissolved Solids
C. Volatile Solids D. Total Solids

211. In complexometric titration, the most common used chelating agent is EDTA
(ethylenediamine tetraacetic acid). EDTA's molecules will combine with metals to form chelate.
EDTA is classified as a?
A. Bidentate ligand
B. Hexadentate ligand
C. Tetradentate ligand
D. Monodentate ligand

212. The light source used in the visible range to 340-1000 nm.
A.deuterium B. nerst blower C. tungsten D. incandescent

213. The % T of a solution in a 2.00 cm cell is 50. Calculate the %T of this solution in a 1.0 cm
cell path length.
A. 71 B. 19 C. 27 D. 20

214. An air sampling canister was evacuated by the local fire dep’t and brought to the
environmental lab for analysis. It was said that the sample was taken very near the site where a
rusty 55-gal drum was found by some children. A reported unpleasant smell near the site was
reported. Results of gravimetric analysis of the gas in the canister: C – 40%, H- 6.7% , O –
53.33%. What is the liquid in the drum?
A. CH2O B. CH3OH C. CH3CH2O D. none of the above

215. A comparison of measuring equipment against a standard instrument of higher accuracy to

detect, correlate, adjust, rectify and document the accuracy of the instrument being compared.
A. Verification B. Validation C. Calibration D. none of the above

216. The property of a result of a measurement whereby it can be related to appropriate

standards,
generally national or international standards, through an unbroken chain of comparisons.”
A. Calibration B. Accuracy C. Precision D.Traceability
 ANALYTICAL CHEMISTRY PRE-BOARD EXAM

217. A method used to purify individual chemical compounds from mixtures of compounds. It is
often used for preparative applications on scales from micrograms up to kilograms.
A. column chromatography B. paper chromatography
C. Flourescence spectrometry D. AAS
218. The visual output of the chromatograph. In the case of an optimal separation, different
peaks or patterns correspond to different components of the separated mixture.
A. computer display B. chromatography C. chromatogram D. read out

219. Used to purify sufficient quantities of a substance for further use, rather than analysis.
A. analytical chromatography B. preparative chromatography
C. size exclusion chromatography D. Ion chromatography

220. The characteristic time it takes for a particular analyte to pass through the system (from the
column inlet to the detector) under set conditions.
A. end time B. contact time C. retention time D. reaction time

221. The basic operating principle of ________ is to force the analyte through a column of the
stationary phase (usually a tube packed with small spherical particles with a certain surface
chemistry) by pumping a liquid (mobile phase) at high pressure through the column.
A. GC B. SEC C. Gel chromatography D. HPLC

222. Size exclusion chromatography (SEC), is also known as ___________ which separates
particles on the basis of size. It is generally a low resolution chromatography and thus it is often
reserved for the final, "polishing" step of a purification, useful for determining the tertiary
structure and quaternary structure of purified proteins.
A. Reversed phase HPLC (RP-HPLC)
B. Normal Phase HPLC
C. Paper Chromatography
D. Gel permeation chromatography or gel filtration chromatography

223. A type of chromatography where the retention is based on the attraction between solute ions
and charged sites bound to the stationary phase. Ions of the same charge are excluded.
A. analytical chromatography B. preparative chromatography
C. size exclusion chromatography D. Ion chromatography

224. The liquid or gas entering a chromatographic bed (e.g. a column) used to effect a separation
by "elution."
A. eluate B. stationary phase C. buffers D. none of the above

225. The study of the interaction between radiation (electromagnetic radiation , or light, as well
as particle radiation ) and matter .
A. Spectrophotometry B. Spectrometry C. Spectrograph D. Spectroscopy
ANALYTICAL CHEMISTRY PRE-BOARD EXAM

GOOD LUCK