Riboza-fosfat difosfokinaza
| Riboza-fosfat difosfokinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.6.1 | ||||||||
| CAS broj | 9015-83-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Riboza-fosfat difosfokinaza (EC 2.7.6.1, riboza-fosfatna pirofosfokinaza, PRPP sintetaza, fosforibozilpirofosfatna sintetaza, PPRibP sintetaza, PP-riboza P sintetaza, 5-fosforibozil-1-pirofosfatna sintetaza, 5-fosforibozna pirofosforilaza, 5-fosforibozil-alfa-1-pirofosfatna sintetaza, fosforibozil-difosfatna sintetaza, fosforibozilpirofosfatna sintaza, pirofosforibozilfosfatna sintetaza, ribofosfatna pirofosfokinaza, riboza-5-fosfatna pirofosfokinaza) je enzim sa sistematskim imenom ATP:D-riboza-5-fosfat difosfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
dATP takođe može da deluje kao donor.
- ↑ Hughes, D.E. and Williamson, D.H. (1952). „Some properties of glutaminase of Clostridium welchii”. Biochem. J. 51: 45-55. PMID 14944530.
- ↑ Hurlbert, R.B. and Reichard, P. (1955). „The conversion of orotic acid to uridine nucleotides in vitro”. Acta Chem. Scand. 9: 251-262.
- ↑ Remy, C.N., Remy, W.T. and Buchanan, J.M. (1955). „Biosynthesis of the purines. VIII. Enzymatic synthesis and utilization of α-5-phosphoribosylpyrophosphate”. J. Biol. Chem. 217: 885-895. PMID 13271449.
- ↑ Switzer, R.L. (1969). „Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium”. J. Biol. Chem. 244: 2854-2863. PMID 4306285.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.