Python AI Agent Frameworks for Mac

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Browse free open source Python AI Agent Frameworks for Mac and projects below. Use the toggles on the left to filter open source Python AI Agent Frameworks for Mac by OS, license, language, programming language, and project status.

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    eProcurement Software

    Enterprises and companies seeking a solution to manage all their procurement operations and processes

    eBuyerAssist by Eyvo is a cloud-based procurement solution designed for businesses of all sizes and industries. Fully modular and scalable, it streamlines the entire procurement lifecycle—from requisition to fulfillment. The platform includes powerful tools for strategic sourcing, supplier management, warehouse operations, and contract oversight. Additional modules cover purchase orders, approval workflows, inventory and asset management, customer orders, budget control, cost accounting, invoice matching, vendor credit checks, and risk analysis. eBuyerAssist centralizes all procurement functions into a single, easy-to-use system—improving visibility, control, and efficiency across your organization. Whether you're aiming to reduce costs, enhance compliance, or align procurement with broader business goals, eBuyerAssist helps you get there faster, smarter, and with measurable results.
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  • 1
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 10 This Week
    Last Update:
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  • 2
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 9 This Week
    Last Update:
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  • 3
    Letta

    Letta

    Letta (formerly MemGPT) is a framework for creating LLM services

    Letta is an AI-powered task automation framework designed to handle workflow automation, natural language commands, and AI-driven decision-making.
    Downloads: 8 This Week
    Last Update:
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  • 4
    DSPy

    DSPy

    DSPy: The framework for programming—not prompting—language models

    Developed by the Stanford NLP Group, DSPy (Declarative Self-improving Python) is a framework that enables developers to program language models through compositional Python code rather than relying solely on prompt engineering. It facilitates the construction of modular AI systems and provides algorithms for optimizing prompts and weights, enhancing the quality and reliability of language model outputs.
    Downloads: 5 This Week
    Last Update:
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  • 5
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 5 This Week
    Last Update:
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  • 6
    Composio

    Composio

    Composio equip's your AI agents & LLMs

    Empower your AI agents with Composio - a platform for managing and integrating tools with LLMs & AI agents using Function Calling. Equip your agent with high-quality tools & integrations without worrying about authentication, accuracy, and reliability in a single line of code.
    Downloads: 3 This Week
    Last Update:
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  • 7
    LangGraph

    LangGraph

    Build resilient language agents as graphs

    LangGraph is a library for building stateful, multi-actor applications with LLMs, used to create agent and multi-agent workflows. Compared to other LLM frameworks, it offers these core benefits: cycles, controllability, and persistence. LangGraph allows you to define flows that involve cycles, essential for most agentic architectures, differentiating it from DAG-based solutions. As a very low-level framework, it provides fine-grained control over both the flow and state of your application, crucial for creating reliable agents. Additionally, LangGraph includes built-in persistence, enabling advanced human-in-the-loop and memory features.
    Downloads: 3 This Week
    Last Update:
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  • 8
    Notte

    Notte

    Opensource browser using agents

    Notte is an open-source browser framework that enables the development and deployment of web-based AI agents. It introduces a perception layer that transforms web pages into structured, navigable maps described in natural language, allowing agents to interact with the internet more effectively. Notte is designed for building scalable and efficient browser-based AI applications.
    Downloads: 3 This Week
    Last Update:
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  • 9
    uAgents

    uAgents

    A fast and lightweight framework for creating decentralized agents

    uAgents is a library developed by Fetch.ai that allows for creating autonomous AI agents in Python. With simple and expressive decorators, you can have an agent that performs various tasks on a schedule or takes action on various events.
    Downloads: 3 This Week
    Last Update:
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    Desktop and Mobile Device Management Software

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  • 10
    CrewAI

    CrewAI

    Framework for orchestrating role-playing, autonomous AI agents

    Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks. The power of AI collaboration has too much to offer. CrewAI is designed to enable AI agents to assume roles, share goals, and operate in a cohesive unit - much like a well-oiled crew. Whether you're building a smart assistant platform, an automated customer service ensemble, or a multi-agent research team, CrewAI provides the backbone for sophisticated multi-agent interactions.
    Downloads: 2 This Week
    Last Update:
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  • 11
    Director

    Director

    AI video agents framework for next-gen video interactions

    Director is a video database management system designed to organize, search, and retrieve large collections of video content efficiently.
    Downloads: 2 This Week
    Last Update:
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  • 12
    InstantCharacter

    InstantCharacter

    Personalize Any Characters with a Scalable Diffusion Transformer

    InstantCharacter is a tuning-free diffusion transformer framework created by Tencent Hunyuan / InstantX team, which enables generating images of a specific character (subject) from a single reference image, preserving identity and character features. Uses adapters, so full fine-tuning of the base model is not required. Demo scripts and pipeline API (via infer_demo.py, pipeline.py) included. It works by adapting a base image generation model with a lightweight adapter so that you can produce character-preserving generations in various downstream tasks (e.g. changing pose, clothing, scene) without needing full model fine-tuning. Works with huggingface/transformers/diffusers ecosystems.
    Downloads: 2 This Week
    Last Update:
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  • 13
    IntentKit

    IntentKit

    An open and fair framework for everyone to build AI agents

    IntentKit is a natural language understanding (NLU) library focused on intent recognition and entity extraction, enabling developers to build conversational AI applications.
    Downloads: 2 This Week
    Last Update:
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  • 14
    PraisonAI

    PraisonAI

    PraisonAI application combines AutoGen and CrewAI or similar framework

    PraisonAI application combines AutoGen and CrewAI or similar frameworks into a low-code solution for building and managing multi-agent LLM systems, focusing on simplicity, customization, and efficient human-agent collaboration. Chat with your ENTIRE Codebase. Praison AI, leveraging both AutoGen and CrewAI or any other agent framework, represents a low-code, centralized framework designed to simplify the creation and orchestration of multi-agent systems for various LLM applications, emphasizing ease of use, customization, and human-agent interaction.
    Downloads: 2 This Week
    Last Update:
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  • 15
    TrustGraph

    TrustGraph

    Deploy reasoning AI agents powered by agentic graph RAG in minutes

    TrustGraph is an AI-driven framework designed to assess and visualize trust relationships within networks, aiding in the analysis of trustworthiness and influence among entities.
    Downloads: 2 This Week
    Last Update:
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  • 16
    AgentPilot

    AgentPilot

    A versatile workflow automation platform to create AI workflows

    AgentPilot is a versatile workflow automation platform designed to help users create, organize, and execute AI-driven workflows. It supports everything from simple tasks using a single large language model (LLM) to complex multi-step processes. The platform features a user-friendly interface that allows for real-time interaction with workflows, and it supports flexible configurations, including branching workflows and customizable user interfaces. Users can also schedule tasks based on natural language time expressions and integrate various tools to enhance their workflows.
    Downloads: 27 This Week
    Last Update:
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  • 17
    Agent Payments Protocol (AP2)

    Agent Payments Protocol (AP2)

    Building a Secure and Interoperable Future for AI-Driven Payments

    AP2 is a project released by Google’s “Agentic Commerce” initiative, focusing on a protocol and reference implementation for agent-driven or AI-mediated payments. In effect, AP2 aims to define a secure, interoperable protocol that allows software agents to act on behalf of users—making payments or shopping decisions autonomously—while preserving necessary security, auditability, and trust. The repository contains sample scenarios (in Python, Android, etc.) that illustrate how agents, servers, and payments flows would work under the protocol. It includes “types” definitions (the core message and object schema) and example agent implementations to demonstrate the mechanics of agent-to-agent and agent-to-server interactions. The design emphasizes flexibility: although their samples use a particular Agent Development Kit (ADK) or runtime, the protocol is intended to be independent of those choices.
    Downloads: 1 This Week
    Last Update:
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  • 18
    Atomic Agents

    Atomic Agents

    Building AI agents, atomically

    The Atomic Agents framework is designed around the concept of atomicity to be an extremely lightweight and modular framework for building Agentic AI pipelines and applications without sacrificing developer experience and maintainability. The framework provides a set of tools and agents that can be combined to create powerful applications. It is built on top of Instructor and leverages the power of Pydantic for data and schema validation and serialization. All logic and control flows are written in Python, enabling developers to apply familiar best practices and workflows from traditional software development without compromising flexibility or clarity.
    Downloads: 1 This Week
    Last Update:
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  • 19
    GPT Researcher

    GPT Researcher

    LLM based autonomous agent that does online comprehensive research

    Say Hello to GPT Researcher, your AI agent for rapid insights and comprehensive research. GPT Researcher is the leading autonomous agent that takes care of everything from accurate source gathering to organization of research results.
    Downloads: 1 This Week
    Last Update:
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  • 20
    Langroid

    Langroid

    Harness LLMs with Multi-Agent Programming

    Given the remarkable abilities of recent Large Language Models (LLMs), there is an unprecedented opportunity to build intelligent applications powered by this transformative technology. The top question for any enterprise is: how best to harness the power of LLMs for complex applications? For technical and practical reasons, building LLM-powered applications is not as simple as throwing a task at an LLM system and expecting it to do it. Effectively leveraging LLMs at scale requires a principled programming framework. In particular, there is often a need to maintain multiple LLM conversations, each instructed in different ways, and "responsible" for different aspects of a task.
    Downloads: 1 This Week
    Last Update:
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  • 21
    OpenAI Agents SDK

    OpenAI Agents SDK

    A lightweight, powerful framework for multi-agent workflows

    The OpenAI Agents Python SDK is a powerful yet lightweight framework for developing multi-agent workflows. This framework enables developers to create and manage agents that can coordinate tasks autonomously, using a set of instructions, tools, guardrails, and handoffs. The SDK allows users to configure workflows in which agents can pass control to other agents as necessary, ensuring dynamic task management. It also includes a built-in tracing system for tracking, debugging, and optimizing agent activities.
    Downloads: 1 This Week
    Last Update:
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  • 22
    Parlant

    Parlant

    The behavior guidance framework for customer-facing LLM agents

    Parlant is a lightweight speech-to-text and text-to-speech framework designed for real-time AI-driven voice applications.
    Downloads: 1 This Week
    Last Update:
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  • 23
    Phidata

    Phidata

    Build multi-modal Agents with memory, knowledge, tools and reasoning

    Phidata is an open source platform for building, deploying, and monitoring AI agents. It enables users to create domain-specific agents with memory, knowledge, and external tools, enhancing AI capabilities for various tasks. The platform supports a range of large language models and integrates seamlessly with different databases, vector stores, and APIs. Phidata offers pre-configured templates to accelerate development and deployment, allowing users to quickly go from building agents to shipping them into production. It includes features like real-time monitoring, agent evaluations, and performance optimization tools, ensuring the reliability and scalability of AI solutions. Phidata also allows developers to bring their own cloud infrastructure, offering flexibility for custom setups. The platform provides robust support for enterprises, including security features, agent guardrails, and automated DevOps for smoother deployment processes.
    Downloads: 1 This Week
    Last Update:
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  • 24
    Quark Agent

    Quark Agent

    Quark Agent - Your AI-powered Android APK Analyst

    With Quark Agent, you can perform analyses using only natural language. It creates Quark Script code following your ideas and adjusts the code promptly as you provide feedback.
    Downloads: 1 This Week
    Last Update:
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  • 25
    Qwen-Agent

    Qwen-Agent

    Agent framework and applications built upon Qwen>=3.0

    Qwen-Agent is a framework for building applications / agents using Qwen models (version 3.0+). It provides components for instruction following, tool usage (function calling), planning, memory, RAG (retrieval augmented generation), code interpreter, etc. It ships with example applications (Browser Assistant, Code Interpreter, Custom Assistant), supports GUI front-ends, backends, server setups. Agent workflow can maintain context / memory to perform multi-turn or more complex logic over time. It acts as the backend for Qwen Chat among other use cases. Built-in Code Interpreter tool that can execute code (locally) as part of agent workflows.
    Downloads: 1 This Week
    Last Update:
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