Open Source Python MCP Clients

mcp-use is an open source development platform offering SDKs, cloud infrastructure, and a developer-friendly control plane for building, managing, and deploying AI agents that leverage the Model Context Protocol (MCP). It enables connection to multiple MCP servers, each exposing specific tool capabilities like browsing, file operations, or specialized integrations, through a unified MCPClient. Developers can create custom agents (via MCPAgent) that dynamically select the most appropriate server for each task using configurable pipelines or a built-in server manager. It simplifies authentication, access control, audit logging, observability, sandboxed runtime environments, and deployment workflows, whether self-hosted or managed, making MCP development production-ready. With integrations for popular frameworks like LangChain (Python) and LangChain.js (TypeScript), mcp-use accelerates the creation of tool-enabled AI agents.

Nerve is a developer-friendly Agent Development Kit (ADK) that utilizes YAML and a CLI to define, run, orchestrate, and evaluate LLM-driven agents. It supports declarative setups, tool integration, workflow pipelines, and both MCP client and server roles. Nerve is a simple yet powerful Agent Development Kit (ADK) to build, run, evaluate, and orchestrate LLM-based agents using just YAML and a CLI. It’s designed for technical users who want programmable, auditable, and reproducible automation using large language models. Define agents using a clean YAML format: system prompt, task, tools, and variables — all in one file.