Trump administration to cut billions in medical research funding
US
Alaska plane crash: remains of all 10 victims have been recovered, authorities say
Boxing
Irish boxer John Cooney dies aged 28, one week after suffering injury in bout
US
Trump cuts aid to South Africa over ‘racial discrimination’ against Afrikaners
DRC
Rwandan and Congolese leaders join summit on eastern DRC conflict
US
Mexico authorities order factory cleanup after Guardian toxic waste investigation
Oasis
Dreams ‘crushed’ as Ticketmaster cancels fans’ Oasis ’25 tickets
UK
Hundreds protest against Chinese ‘mega-embassy’ in London
UK
Hollyoaks actor Callum Kerr issues statement after death of mother and her husband in France
News in focus
Gaza
‘This time, we stay’: the Palestinian families vowing not to leave Gaza
Russia
‘Many teachers don’t want to do this, but they’re trapped’: film shows extent of Putin indoctrination in Russian schools
Two years after he started documenting the effect of the Ukraine war on his pupils, Pavel Talankin reveals how it led to accolade – and exile from home
Kosovo
Kosovo goes to the polls as the shadow of Trump looms large
Fears of partition that arose during Trump’s first administration have re-emerged as PM Albin Kurti navigates tense relations with both US and EU
Spotlight
Syria
‘Woman, life, freedom’: the Syrian feminists who forged a new world in a land of war
In a society riven by conflict and misogyny, the autonomous region of Rojava has a government with perhaps the most complete gender equality in the world
Ask Philippa
I feel happier and healthier when not around my mother
Society
Can we break the anxiety habit?
Writer and therapist Owen O’Kane believes we have become addicted to feeling anxious. Here, he explains how he learned to manage his fears
Film
‘They were trying to do 200 different poses during power cuts’: Bridget Jones director takes on The Joy of Sex
In the 1970s a ‘nude biologist brandishing a cigar’ wrote a game-changing sex manual. Now, ‘Shazza’ is putting his story on the big screen
Wendy Ide's film of the week
The Seed of the Sacred Fig – Mohammad Rasoulof’s fearless drama is a damning indictment of the Iranian regime
Travel
From world’s ‘roughest wilderness hotel’ to a cosy Cotswolds hideaway: 10 adventure stays in Europe
Books
‘We’re not doing the thing we’re built to do’: Agnes Callard, the philosopher living life according to Socrates
Splat’s entertainment: I watched Rotten Tomatoes’ 40 lowest-rated films to find out which was worst
Our brave victim writer sits through the film site’s 0%ers to see what makes a bad movie. Will she emerge with her sanity intact – and are all these flops really so bad?
Art
Matisse’s muse: new exhibition dedicated to the illegitimate daughter he spent a lifetime painting
Books interview
Andrew O’Hagan: ‘A kind of Dickens and Zola energy was pulsing’
Television
‘Sometimes it’s fabulous, sometimes it’s Lord of the Flies’: behind the scenes of The White Lotus season three
Going out
Come early, leave early: a gen X dance party that ends at 10pm is taking off across the US
Jazz
Moses Yoofee Trio: MYT review – brilliantly explosive jazz
Lifestyle
Ageing
Anti-ageing jabs – they can rejuvenate mice, but will they work on humans?
Senescent cells power the body’s ageing process, and scientists are developing treatments to annihilate them
The moment I knew
I was mourning the end of my summer fling – then a parcel arrived at my door
Fashion
The sneakerina: must-have item or step too far for hybrid fashion?
We love
Fashion fixes for the week ahead – in pictures
Family
‘My time with my son is more limited – and more precious’: older fathers on having kids in their 60s and 70s
Well actually
Constantly scrolling on your phone? Why we can’t stand feeling bored
Take part
Santorini
Have you been affected by the earthquakes on Santorini?
Tattoos
Do you have a tattoo you regret?
US homeowners
Tell us how you are coping with the rising costs of owning your home
Coronavirus
Share your experiences ahead of the fifth anniversary of Covid being declared as a global pandemic
Loads more stories and moves focus to first new story.
AstraZeneca, Whitehall, and a failed £450m deal for the next generation in vaccines. What went wrong?
When the pharma firm cancelled plans for a major expansion of its Merseyside plant last month, there was no shortage of questions – or blame – over responsibility
Science
Elon Musk put a chip in this paralysed man’s brain. Now he can move things with his mind. Should we be amazed - or terrified?
Trump administration
US equality chief fired by Trump condemns ‘demonization of the term DEI’
Analysis
Rebuilding shattered Gaza may require a new Marshall plan
Our unequal earth
Western food was unhealthy and costly. So they turned back to bison and mushrooms
Oregon
Food security project that helps farm workers springs from ashes of wildfires
Marina Hyde on Kanye and Bianca; the woman who lives without money; Roman Kemp on tattoos and mental health; and Philippa Perry on ‘chaotic’ partners – podcast
Football Weekly
Liverpool smash Spurs to reach League Cup final – Football Weekly Extra
Politics Weekly UK
Special episode: Behind the scenes of David Lammy’s Ukraine trip
The Audio Long Read
Tokyo drift: what happens when a city stops being the future? – podcast
Today in Focus
Going bald in an increasingly hairy world – podcast
Wayne Tippetts’s shot of young Bangladeshi women preparing for a Gaye Holud ceremony is part of a series exploring a pivotal moment in the neighbourhood’s history
Drawing
Where the heart is: the artist memorialising homes lost in the LA fires
Twenty photographs of the week
Palestinians return to Gaza, the shooting in Sweden, earthquakes in Greece and Charli XCX at the Grammy awards
Flashback
Matt Goss looks back: ‘I’d like another Bros experience. Something massive, Bros on steroids. Bigger, the biggest’